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- W1983165764 abstract "Id helix—loop—helix proteins function at a general level as positive regulators of cell growth and as negative regulators of cell differentiation. They act as dominant—negative antagonists of other helix—loop—helix transcription factors, which drive cell lineage commitment and differentiation in diverse cell types of higher eukaryotes. In addition, the functions of Id proteins are integrated with cell-cycle-regulatory pathways orchestrated by cyclin-dependent kinases and the retinoblastoma protein. Here, some of the recent advances that highlight the importance of Id proteins as regulatory intermediates for coordinating differentiation-linked gene expression with cell-cycle control in response to extracellular signalling are reviewed." @default.
- W1983165764 created "2016-06-24" @default.
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- W1983165764 date "1998-02-01" @default.
- W1983165764 modified "2023-10-17" @default.
- W1983165764 title "Id helix—loop—helix proteins in cell growth and differentiation" @default.
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- W1983165764 doi "https://doi.org/10.1016/s0962-8924(98)80013-5" @default.
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