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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983171965> ?p ?o ?g. }

• W1983171965 endingPage "6760" @default.
• W1983171965 startingPage "6756" @default.
• W1983171965 abstract "In our pursuit to identify selective ligands for Bz/GABAA receptor subtypes, a novel pyrazolo[1,5-a]pyrimidine derivative (4), the azaisostere of zolpidem, was synthesized and evaluated in vitro on bovine brain homogenate and on recombinant benzodiazepine receptors (αxβ2/3γ2, x = 1−3, 5) expressed in HEK293 cells. Compound 4 displayed affinity only for α1β2γ2 subtype (Ki = 31 nM), and in an in-depth, in vivo study it revealed sedative and anxiolytic-like properties without any amnesic and myorelaxant effects in rodents." @default.
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• W1983171965 date "2005-09-23" @default.
• W1983171965 modified "2023-10-07" @default.
• W1983171965 title "A Novel Selective GABA_A α1 Receptor Agonist Displaying Sedative and Anxiolytic-like Properties in Rodents" @default.
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• W1983171965 doi "https://doi.org/10.1021/jm058002n" @default.
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