Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983184807> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W1983184807 endingPage "1" @default.
- W1983184807 startingPage "1" @default.
- W1983184807 abstract "Clonazepam is a benzodiazepine (BZD) authorized for treatment of epilepsy in France. Several evidences for clonazepam abuse liability and offlabel use were observed. Authorities changed the legislation to make clonazepam diversion more difficult. We asked if the three successive law changes between 2008 and 2011 have influenced clonazepam use and abuse. To assess the impact of recent legislation changes on clonazepam abuse in the Paris Metropolitan Region. A quantitative analysis of all clonazepam data from 2003 to 2012 of three epidemiological tools has been performed: NOT'S is a CEIP database of spontaneous NOTifications of drug abuse and dependence. Observation of Illegal Drugs and Misuse of Psychotropic Medications (OPPIDUM), data from French health reimbursement system (FHRS) for all the country. We aimed to compare clonazepam misuse and abuse evolution with diazepam and flunitrazepam to assess the legislation impact on clonazepam. In NOT'S, between 2003 and 2007 the proportion of clonazepam misuse ans abuse seems to be stable (15% ±2 of all notifications). Clonazepam abuse increases between 2007 and 2010 (up to 30%) then starts to decrease after 2010 until now (23% of all notifications). These results are consistents with data from the FHRS, whereas in the OPPIDUM survey clonazepam use seems to be stable in addiction centres. Diazepam use is constantly increasing in the 3 epidemiologic tools whereas flunitrazepam use is stable or slowly decreasing. Our results show an influence of the legislation on the misuse of clonazepam particularly in the untreated addicted population." @default.
- W1983184807 created "2016-06-24" @default.
- W1983184807 creator A5010845327 @default.
- W1983184807 creator A5013855686 @default.
- W1983184807 creator A5046872712 @default.
- W1983184807 creator A5065812033 @default.
- W1983184807 date "2014-01-01" @default.
- W1983184807 modified "2023-10-16" @default.
- W1983184807 title "EPA-0437 – Impact of legislation change on clonazepam abuse" @default.
- W1983184807 doi "https://doi.org/10.1016/s0924-9338(14)77857-5" @default.
- W1983184807 hasPublicationYear "2014" @default.
- W1983184807 type Work @default.
- W1983184807 sameAs 1983184807 @default.
- W1983184807 citedByCount "0" @default.
- W1983184807 crossrefType "journal-article" @default.
- W1983184807 hasAuthorship W1983184807A5010845327 @default.
- W1983184807 hasAuthorship W1983184807A5013855686 @default.
- W1983184807 hasAuthorship W1983184807A5046872712 @default.
- W1983184807 hasAuthorship W1983184807A5065812033 @default.
- W1983184807 hasConcept C118552586 @default.
- W1983184807 hasConcept C126322002 @default.
- W1983184807 hasConcept C170493617 @default.
- W1983184807 hasConcept C17744445 @default.
- W1983184807 hasConcept C199539241 @default.
- W1983184807 hasConcept C2777351106 @default.
- W1983184807 hasConcept C2778173252 @default.
- W1983184807 hasConcept C2779426884 @default.
- W1983184807 hasConcept C2781442855 @default.
- W1983184807 hasConcept C71924100 @default.
- W1983184807 hasConceptScore W1983184807C118552586 @default.
- W1983184807 hasConceptScore W1983184807C126322002 @default.
- W1983184807 hasConceptScore W1983184807C170493617 @default.
- W1983184807 hasConceptScore W1983184807C17744445 @default.
- W1983184807 hasConceptScore W1983184807C199539241 @default.
- W1983184807 hasConceptScore W1983184807C2777351106 @default.
- W1983184807 hasConceptScore W1983184807C2778173252 @default.
- W1983184807 hasConceptScore W1983184807C2779426884 @default.
- W1983184807 hasConceptScore W1983184807C2781442855 @default.
- W1983184807 hasConceptScore W1983184807C71924100 @default.
- W1983184807 hasLocation W19831848071 @default.
- W1983184807 hasOpenAccess W1983184807 @default.
- W1983184807 hasPrimaryLocation W19831848071 @default.
- W1983184807 hasRelatedWork W1538421298 @default.
- W1983184807 hasRelatedWork W1966211518 @default.
- W1983184807 hasRelatedWork W1967262540 @default.
- W1983184807 hasRelatedWork W1972559823 @default.
- W1983184807 hasRelatedWork W1975761280 @default.
- W1983184807 hasRelatedWork W2023509138 @default.
- W1983184807 hasRelatedWork W2029300670 @default.
- W1983184807 hasRelatedWork W2051589181 @default.
- W1983184807 hasRelatedWork W2090803718 @default.
- W1983184807 hasRelatedWork W2416932450 @default.
- W1983184807 hasVolume "29" @default.
- W1983184807 isParatext "false" @default.
- W1983184807 isRetracted "false" @default.
- W1983184807 magId "1983184807" @default.
- W1983184807 workType "article" @default.