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• W1983202382 endingPage "285" @default.
• W1983202382 startingPage "280" @default.
• W1983202382 abstract "Lipid bilayers provide a solute-proof barrier that is widely used in living systems. It has long been recognized that the structural changes of lipids during the phase transition from bilayer to non-bilayer have striking similarities with those accompanying membrane fusion processes. In spite of this resemblance, the numerous quantitative studies on pure lipid bilayers are difficult to apply to real membranes. One reason is that in living matter, instead of pure lipids, lipid mixtures are involved and there is currently no model that establishes the connection between pure lipids and lipid mixtures. Here, we make this connection by showing how to obtain (i) the short-range repulsion between bilayers made of lipid mixtures and, (ii) the pressure at which transition from bilayer phase to non-bilayer phases occur. We validated our models by fitting the experimental data of several lipid mixtures to the theoretical data calculated based on our model. These results provide a useful tool to quantitatively predict the behavior of complex membranes at low hydration." @default.
• W1983202382 created "2016-06-24" @default.
• W1983202382 creator A5045553702 @default.
• W1983202382 creator A5068421067 @default.
• W1983202382 date "2010-03-01" @default.
• W1983202382 modified "2023-09-30" @default.
• W1983202382 title "Quantification of phase transitions of lipid mixtures from bilayer to non-bilayer structures: Model, experimental validation and implication on membrane fusion" @default.
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• W1983202382 doi "https://doi.org/10.1016/j.chemphyslip.2009.12.002" @default.
• W1983202382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20018184" @default.
• W1983202382 hasPublicationYear "2010" @default.
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