FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983246378> ?p ?o ?g. }

• W1983246378 endingPage "49" @default.
• W1983246378 startingPage "44" @default.
• W1983246378 abstract "Abstract CD8+ cytotoxic T lymphocytes (CTL) recognize peptide antigens in the context of class I MHC antigen molecules. To identify peptides capable of eliciting anti-Chlamydia trachomatis CTL responses, 13 synthetic peptides conforming to human leucocyte antigen (HLA)-B8- or -B35-predicted binding motifs were synthesized using sequences based on C. trachomatis major outer membrane protein (MOMP) and heat shock protein 60 (hsp60). Two of 11 HLA-B35-predicted binding peptides were able to stabilize HLA-B35 in an in vitro binding assay. All peptides were tested in CTL assays using peripheral blood mononuclear cells (PBMC) isolated from 26 HLA-B8 or -B35 individuals resident in a trachoma-endemic community. Responses to MOMP and hsp60 peptides were identified in a minority of both HLA-B8 and -B35 individuals. Two of 12 HLA-B8 subjects responded to MOMP and 1/13 to hsp60 peptides. Responses in HLA-B35 subjects were similar, 1/13 subjects responding to MOMP and 2/13 to hsp60 peptides. CTL responses were observed only in children resolving current infection and in adults without scarring of the conjunctiva. These results suggest that anti-chlamydial CTL occur at low levels in peripheral blood, but may be important in the resolution of naturally acquired human ocular chlamydial infection." @default.
• W1983246378 created "2016-06-24" @default.
• W1983246378 creator A5009374844 @default.
• W1983246378 creator A5012387962 @default.
• W1983246378 creator A5024658487 @default.
• W1983246378 creator A5055354943 @default.
• W1983246378 creator A5057509814 @default.
• W1983246378 creator A5067192172 @default.
• W1983246378 creator A5088225687 @default.
• W1983246378 date "1997-01-01" @default.
• W1983246378 modified "2023-09-27" @default.
• W1983246378 title "Synthetic peptides based on <i>Chlamydia trachomatis</i> antigens identify cytotoxic T lymphocyte responses in subjects from a trachoma-endemic population" @default.
• W1983246378 cites W111462511 @default.
• W1983246378 cites W1502443399 @default.
• W1983246378 cites W1506623892 @default.
• W1983246378 cites W1533714304 @default.
• W1983246378 cites W1600829515 @default.
• W1983246378 cites W1954779485 @default.
• W1983246378 cites W1977847455 @default.
• W1983246378 cites W2002375590 @default.
• W1983246378 cites W2039998215 @default.
• W1983246378 cites W2045377848 @default.
• W1983246378 cites W2055488100 @default.
• W1983246378 cites W2057270390 @default.
• W1983246378 cites W2100952331 @default.
• W1983246378 cites W2101305284 @default.
• W1983246378 cites W2108564681 @default.
• W1983246378 cites W2110560382 @default.
• W1983246378 cites W2128429564 @default.
• W1983246378 cites W2132612515 @default.
• W1983246378 cites W2139441535 @default.
• W1983246378 cites W2142680679 @default.
• W1983246378 cites W2148828140 @default.
• W1983246378 cites W2158228685 @default.
• W1983246378 cites W2159409765 @default.
• W1983246378 cites W2164407992 @default.
• W1983246378 cites W2165487319 @default.
• W1983246378 cites W2168352947 @default.
• W1983246378 cites W2336980357 @default.
• W1983246378 cites W2412095377 @default.
• W1983246378 cites W2414612953 @default.
• W1983246378 cites W2470165674 @default.
• W1983246378 doi "https://doi.org/10.1046/j.1365-2249.1997.2511129.x" @default.
• W1983246378 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1904554" @default.
• W1983246378 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9010255" @default.
• W1983246378 hasPublicationYear "1997" @default.
• W1983246378 type Work @default.
• W1983246378 sameAs 1983246378 @default.
• W1983246378 citedByCount "32" @default.
• W1983246378 countsByYear W19832463782013 @default.
• W1983246378 countsByYear W19832463782014 @default.
• W1983246378 countsByYear W19832463782015 @default.
• W1983246378 countsByYear W19832463782017 @default.
• W1983246378 countsByYear W19832463782019 @default.
• W1983246378 crossrefType "journal-article" @default.
• W1983246378 hasAuthorship W1983246378A5009374844 @default.
• W1983246378 hasAuthorship W1983246378A5012387962 @default.
• W1983246378 hasAuthorship W1983246378A5024658487 @default.
• W1983246378 hasAuthorship W1983246378A5055354943 @default.
• W1983246378 hasAuthorship W1983246378A5057509814 @default.
• W1983246378 hasAuthorship W1983246378A5067192172 @default.
• W1983246378 hasAuthorship W1983246378A5088225687 @default.
• W1983246378 hasBestOaLocation W19832463782 @default.
• W1983246378 hasConcept C142724271 @default.
• W1983246378 hasConcept C147483822 @default.
• W1983246378 hasConcept C147969180 @default.
• W1983246378 hasConcept C154317977 @default.
• W1983246378 hasConcept C159047783 @default.
• W1983246378 hasConcept C167672396 @default.
• W1983246378 hasConcept C188280979 @default.
• W1983246378 hasConcept C202751555 @default.
• W1983246378 hasConcept C203014093 @default.
• W1983246378 hasConcept C2777034029 @default.
• W1983246378 hasConcept C2777391075 @default.
• W1983246378 hasConcept C2908647359 @default.
• W1983246378 hasConcept C54355233 @default.
• W1983246378 hasConcept C71924100 @default.
• W1983246378 hasConcept C86803240 @default.
• W1983246378 hasConcept C89423630 @default.
• W1983246378 hasConcept C99454951 @default.
• W1983246378 hasConceptScore W1983246378C142724271 @default.
• W1983246378 hasConceptScore W1983246378C147483822 @default.
• W1983246378 hasConceptScore W1983246378C147969180 @default.
• W1983246378 hasConceptScore W1983246378C154317977 @default.
• W1983246378 hasConceptScore W1983246378C159047783 @default.
• W1983246378 hasConceptScore W1983246378C167672396 @default.
• W1983246378 hasConceptScore W1983246378C188280979 @default.
• W1983246378 hasConceptScore W1983246378C202751555 @default.
• W1983246378 hasConceptScore W1983246378C203014093 @default.
• W1983246378 hasConceptScore W1983246378C2777034029 @default.
• W1983246378 hasConceptScore W1983246378C2777391075 @default.
• W1983246378 hasConceptScore W1983246378C2908647359 @default.
• W1983246378 hasConceptScore W1983246378C54355233 @default.
• W1983246378 hasConceptScore W1983246378C71924100 @default.
• W1983246378 hasConceptScore W1983246378C86803240 @default.
• W1983246378 hasConceptScore W1983246378C89423630 @default.
• W1983246378 hasConceptScore W1983246378C99454951 @default.
• W1983246378 hasIssue "1" @default.

• next