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• W1983248251 abstract "It has been proposed that sleep disturbances, especially reduced delta sleep, are related to a poor outcome in schizophrenia. To determine whether long-term treatment with neuroleptics can promote sleep disturbances by increasing the risk of a nocturnal myoclonus syndrome (NMS) (=periodic movements in sleep) related insomnia, we performed all-night polysomnography in 10 chronically ill schizophrenic patients who had been under neuroleptic therapy for a mean of 27 years. NMS-related insomnia was detected in all 10 patients. Potential pathophysiological relationships between long-term neuroleptic therapy and NMS occurrence are discussed. Our findings suggest that long-term administration of neuroleptics favours the appearance of insomnia. Copyright © 2000 John Wiley & Sons, Ltd." @default.
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• W1983248251 date "2000-02-01" @default.
• W1983248251 modified "2023-10-18" @default.
• W1983248251 title "Can chronic neuroleptic treatment promote sleep disturbances in elderly schizophrenic patients?" @default.
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• W1983248251 doi "https://doi.org/10.1002/(sici)1099-1166(200002)15:2<170::aid-gps88>3.0.co;2-h" @default.
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