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- W1983252534 abstract "Transformed non-Hodgkin lymphoma (TL) arising from follicular lymphoma carries a poor prognosis, and the median survival time after transformation is approximately 10 to 12 months. Standard chemotherapy and radioimmunotherapy have offered promising responses; however, the duration of response does not appear to last long. Several studies evaluating the role of autologous stem cell transplantation (auto-SCT) as a salvage regimen have been reported, and a subset of patients benefit from this modality of treatment. With an improvement in supportive care, outcome after allogeneic stem cell transplantation (allo-SCT) has been improved significantly over past decades; however, very limited data are available for TL. In the era of emerging novel therapies, the actual timing, optimal conditioning regimens, and long-term impact of the type of stem cell transplantation (auto-SCT vs allo-SCT) is unclear. This review addresses the approaches to the management of patients with TL." @default.
- W1983252534 created "2016-06-24" @default.
- W1983252534 creator A5085325467 @default.
- W1983252534 creator A5088962035 @default.
- W1983252534 date "2011-09-01" @default.
- W1983252534 modified "2023-10-16" @default.
- W1983252534 title "Treatment Options for Transformed Lymphoma: Incorporating Allogeneic Stem Cell Transplantation in a Multimodality Approach" @default.
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- W1983252534 doi "https://doi.org/10.1016/j.bbmt.2011.05.002" @default.
- W1983252534 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3156833" @default.
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