FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983259580> ?p ?o ?g. }

• W1983259580 endingPage "313" @default.
• W1983259580 startingPage "313" @default.
• W1983259580 abstract "Invasive pleomorphic lobular carcinoma (IPLC) is a very rare and distinct morphological variant of invasive lobular carcinoma (ILC), characterized by nuclear atypia and pleomorphism contrasted with the cytologic uniformity of ILC. This study evaluated clinicopathologic characteristics and prognosis of IPLC compared with invasive ductal carcinoma (IDC).We retrospectively reviewed the medical records of 35 patients with IPLC and 6,184 patients with IDC, not otherwise specified. We compared the clinicopathologic characteristics, relapse-free survival (RFS) and disease specific survival (DSS) of patients who were surgically treated between January 1997 and December 2010.Patients with IPLC presented at an older age with larger tumor size, worse histologic grade, higher rates of N3 stage, more multifocal/multicentric tumors, and more nipple-areolar complex involvement than those of patients with IDC. During the follow-up period, the IPLC group experienced five cases (14.3%) of disease recurrence and three cases (8.6%) of disease specific mortality compared with 637 cases (10.4%) of recurrence and 333 cases (5.4%) of disease specific mortality in the IDC group. Univariate analysis using the Kaplan-Meier method revealed that the IPLC group showed a significantly poorer prognosis than that of the IDC group (RFS, p=0.008; DSS, p<0.001). However, after adjusting for clinicopathologic factors, a multivariate analysis showed no statistical differences in RFS (p=0.396) and DSS (p=0.168) between the IPLC and the IDC groups.Our data suggest that patients with IPLC present with poor prognostic factors such as large tumor size, poor histologic grade and advanced stage at diagnosis. These aggressive clinicopathologic characteristics may result in poor clinical outcomes. Although our study could not link IPLC histology to poor prognosis, considering the aggressive characteristics of IPLC, early detection and considerate treatment, including proper surgical and adjuvant intervention, could be helpful for disease progression and survival." @default.
• W1983259580 created "2016-06-24" @default.
• W1983259580 creator A5006385407 @default.
• W1983259580 creator A5021757277 @default.
• W1983259580 creator A5027110002 @default.
• W1983259580 creator A5033852351 @default.
• W1983259580 creator A5041792310 @default.
• W1983259580 creator A5044201544 @default.
• W1983259580 creator A5045318675 @default.
• W1983259580 creator A5051016068 @default.
• W1983259580 creator A5057636290 @default.
• W1983259580 creator A5067006009 @default.
• W1983259580 creator A5078151206 @default.
• W1983259580 creator A5083927091 @default.
• W1983259580 creator A5087484665 @default.
• W1983259580 creator A5088383868 @default.
• W1983259580 date "2012-01-01" @default.
• W1983259580 modified "2023-09-25" @default.
• W1983259580 title "Invasive Pleomorphic Lobular Carcinoma of the Breast: Clinicopathologic Characteristics and Prognosis Compared with Invasive Ductal Carcinoma" @default.
• W1983259580 cites W1892496998 @default.
• W1983259580 cites W1968433465 @default.
• W1983259580 cites W1971476589 @default.
• W1983259580 cites W1977285497 @default.
• W1983259580 cites W1981488582 @default.
• W1983259580 cites W1999571757 @default.
• W1983259580 cites W2000477149 @default.
• W1983259580 cites W2021342315 @default.
• W1983259580 cites W2022034472 @default.
• W1983259580 cites W2031774019 @default.
• W1983259580 cites W2045248888 @default.
• W1983259580 cites W2054027726 @default.
• W1983259580 cites W2069786374 @default.
• W1983259580 cites W2093577980 @default.
• W1983259580 cites W2122751086 @default.
• W1983259580 cites W2151127390 @default.
• W1983259580 cites W2152396350 @default.
• W1983259580 cites W2917026948 @default.
• W1983259580 doi "https://doi.org/10.4048/jbc.2012.15.3.313" @default.
• W1983259580 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3468785" @default.
• W1983259580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23091544" @default.
• W1983259580 hasPublicationYear "2012" @default.
• W1983259580 type Work @default.
• W1983259580 sameAs 1983259580 @default.
• W1983259580 citedByCount "27" @default.
• W1983259580 countsByYear W19832595802013 @default.
• W1983259580 countsByYear W19832595802014 @default.
• W1983259580 countsByYear W19832595802015 @default.
• W1983259580 countsByYear W19832595802016 @default.
• W1983259580 countsByYear W19832595802017 @default.
• W1983259580 countsByYear W19832595802018 @default.
• W1983259580 countsByYear W19832595802019 @default.
• W1983259580 countsByYear W19832595802020 @default.
• W1983259580 countsByYear W19832595802021 @default.
• W1983259580 countsByYear W19832595802022 @default.
• W1983259580 countsByYear W19832595802023 @default.
• W1983259580 crossrefType "journal-article" @default.
• W1983259580 hasAuthorship W1983259580A5006385407 @default.
• W1983259580 hasAuthorship W1983259580A5021757277 @default.
• W1983259580 hasAuthorship W1983259580A5027110002 @default.
• W1983259580 hasAuthorship W1983259580A5033852351 @default.
• W1983259580 hasAuthorship W1983259580A5041792310 @default.
• W1983259580 hasAuthorship W1983259580A5044201544 @default.
• W1983259580 hasAuthorship W1983259580A5045318675 @default.
• W1983259580 hasAuthorship W1983259580A5051016068 @default.
• W1983259580 hasAuthorship W1983259580A5057636290 @default.
• W1983259580 hasAuthorship W1983259580A5067006009 @default.
• W1983259580 hasAuthorship W1983259580A5078151206 @default.
• W1983259580 hasAuthorship W1983259580A5083927091 @default.
• W1983259580 hasAuthorship W1983259580A5087484665 @default.
• W1983259580 hasAuthorship W1983259580A5088383868 @default.
• W1983259580 hasBestOaLocation W19832595801 @default.
• W1983259580 hasConcept C121608353 @default.
• W1983259580 hasConcept C126322002 @default.
• W1983259580 hasConcept C142160229 @default.
• W1983259580 hasConcept C142724271 @default.
• W1983259580 hasConcept C143998085 @default.
• W1983259580 hasConcept C144301174 @default.
• W1983259580 hasConcept C146357865 @default.
• W1983259580 hasConcept C151730666 @default.
• W1983259580 hasConcept C204232928 @default.
• W1983259580 hasConcept C2776372563 @default.
• W1983259580 hasConcept C2777546739 @default.
• W1983259580 hasConcept C2779134260 @default.
• W1983259580 hasConcept C2779296616 @default.
• W1983259580 hasConcept C2780862961 @default.
• W1983259580 hasConcept C2781283455 @default.
• W1983259580 hasConcept C2781289014 @default.
• W1983259580 hasConcept C3020375857 @default.
• W1983259580 hasConcept C38180746 @default.
• W1983259580 hasConcept C530470458 @default.
• W1983259580 hasConcept C71924100 @default.
• W1983259580 hasConcept C86803240 @default.
• W1983259580 hasConceptScore W1983259580C121608353 @default.
• W1983259580 hasConceptScore W1983259580C126322002 @default.
• W1983259580 hasConceptScore W1983259580C142160229 @default.
• W1983259580 hasConceptScore W1983259580C142724271 @default.
• W1983259580 hasConceptScore W1983259580C143998085 @default.
• W1983259580 hasConceptScore W1983259580C144301174 @default.

• next