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- W1983285748 abstract "An efficient “one-pot” conversion of Fmoc-protected amino acids to the ureas in the solid phase is described. This methodology uses McSiCl3 in the presence of Et3N to cleave Fmoc-protected amines directly to their isocyanates. This transformation has been demonstrated on some F'moc-protected amino acids. Trapping of the resin-bound isocyanate by the addition of amines generates the desired amino acid ureas in high HPLC purities." @default.
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- W1983285748 date "1999-06-01" @default.
- W1983285748 modified "2023-09-28" @default.
- W1983285748 title "Solid phase urea synthesis: An efficient and direct conversion of Fmoc-protected amines to ureas" @default.
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- W1983285748 doi "https://doi.org/10.1016/s0040-4039(99)00820-5" @default.
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