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- W1983306484 abstract "Protozoan parasites of the genus Leishmania are responsible for causing a variety of human diseases known as leishmaniasis, which range from self-healing skin lesions to severe infection of visceral organs that are often fatal if left untreated. Leishmania donovani ( L. donovani ), the causative agent of visceral leishmaniasis, exemplifys a devious organism that has developed the ability to invade and replicate within host macrophage. In fact, the parasite has evolved strategies to interfere with a broad range of signaling processes in macrophage that includes Protein Kinase C, the JAK2/STAT1 cascade, and the MAP Kinase pathway. This paper focuses on how L. donovani modulates these signaling pathways that favour its survival and persistence in host cells." @default.
- W1983306484 created "2016-06-24" @default.
- W1983306484 creator A5070387878 @default.
- W1983306484 creator A5070618714 @default.
- W1983306484 date "2011-04-27" @default.
- W1983306484 modified "2023-09-28" @default.
- W1983306484 title "Evasion of Host Defence by<i>Leishmania donovani</i>: Subversion of Signaling Pathways" @default.
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- W1983306484 doi "https://doi.org/10.4061/2011/343961" @default.
- W1983306484 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3199940" @default.
- W1983306484 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22091401" @default.
- W1983306484 hasPublicationYear "2011" @default.
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