FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983353068> ?p ?o ?g. }

• W1983353068 endingPage "4825" @default.
• W1983353068 startingPage "4814" @default.
• W1983353068 abstract "FK506-binding proteins (FKBPs) are cellular receptors for immunosuppressants that belong to a subgroup of proteins, known as immunophilins, with peptidylprolyl cis-trans isomerase (PPIase) activity. Sequence comparison suggested that the HD2-type histone deacetylases and the FKBP-type PPIases may have evolved from a common ancestor enzyme. Here we show that FKBP25 physically associates with the histone deacetylases HDAC1 and HDAC2 and with the HDAC-binding transcriptional regulator YY1. An FKBP25 immunoprecipitated complex contains deacetylase activity, and this activity is associated with the N-terminus of FKBP25, distinct from the FK506/rapamycin-binding domain. Furthermore, FKBP25 can alter the DNA-binding activity of YY1. Together, our data firmly establish a relationship between histone deacetylases and the FKBP enzymes and provide a novel and critical function for the FKBPs." @default.
• W1983353068 created "2016-06-24" @default.
• W1983353068 creator A5004256523 @default.
• W1983353068 creator A5010411205 @default.
• W1983353068 creator A5071411150 @default.
• W1983353068 date "2001-09-03" @default.
• W1983353068 modified "2023-09-30" @default.
• W1983353068 title "The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1" @default.
• W1983353068 cites W1511815964 @default.
• W1983353068 cites W1599851165 @default.
• W1983353068 cites W1689569903 @default.
• W1983353068 cites W1810610903 @default.
• W1983353068 cites W1906465230 @default.
• W1983353068 cites W1965490540 @default.
• W1983353068 cites W1966156883 @default.
• W1983353068 cites W1972047989 @default.
• W1983353068 cites W1972065726 @default.
• W1983353068 cites W1974112332 @default.
• W1983353068 cites W1983274737 @default.
• W1983353068 cites W1986144447 @default.
• W1983353068 cites W1989389781 @default.
• W1983353068 cites W1991085321 @default.
• W1983353068 cites W1993270138 @default.
• W1983353068 cites W1993562598 @default.
• W1983353068 cites W1995902306 @default.
• W1983353068 cites W1998904806 @default.
• W1983353068 cites W2005606747 @default.
• W1983353068 cites W2021820849 @default.
• W1983353068 cites W2023453929 @default.
• W1983353068 cites W2025175795 @default.
• W1983353068 cites W2037998684 @default.
• W1983353068 cites W2040506727 @default.
• W1983353068 cites W2042315437 @default.
• W1983353068 cites W2046693402 @default.
• W1983353068 cites W2052686632 @default.
• W1983353068 cites W2054220939 @default.
• W1983353068 cites W2063460322 @default.
• W1983353068 cites W2071954433 @default.
• W1983353068 cites W2072375912 @default.
• W1983353068 cites W2086021421 @default.
• W1983353068 cites W2091975352 @default.
• W1983353068 cites W2092529264 @default.
• W1983353068 cites W2104788426 @default.
• W1983353068 cites W2106900373 @default.
• W1983353068 cites W2130770262 @default.
• W1983353068 cites W2144206181 @default.
• W1983353068 cites W2146465017 @default.
• W1983353068 cites W2158196711 @default.
• W1983353068 cites W2158301564 @default.
• W1983353068 cites W2160090073 @default.
• W1983353068 cites W2164380111 @default.
• W1983353068 cites W2170249039 @default.
• W1983353068 doi "https://doi.org/10.1093/emboj/20.17.4814" @default.
• W1983353068 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/125595" @default.
• W1983353068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11532945" @default.
• W1983353068 hasPublicationYear "2001" @default.
• W1983353068 type Work @default.
• W1983353068 sameAs 1983353068 @default.
• W1983353068 citedByCount "103" @default.
• W1983353068 countsByYear W19833530682012 @default.
• W1983353068 countsByYear W19833530682013 @default.
• W1983353068 countsByYear W19833530682014 @default.
• W1983353068 countsByYear W19833530682015 @default.
• W1983353068 countsByYear W19833530682016 @default.
• W1983353068 countsByYear W19833530682017 @default.
• W1983353068 countsByYear W19833530682018 @default.
• W1983353068 countsByYear W19833530682019 @default.
• W1983353068 countsByYear W19833530682020 @default.
• W1983353068 countsByYear W19833530682021 @default.
• W1983353068 countsByYear W19833530682022 @default.
• W1983353068 countsByYear W19833530682023 @default.
• W1983353068 crossrefType "journal-article" @default.
• W1983353068 hasAuthorship W1983353068A5004256523 @default.
• W1983353068 hasAuthorship W1983353068A5010411205 @default.
• W1983353068 hasAuthorship W1983353068A5071411150 @default.
• W1983353068 hasBestOaLocation W19833530681 @default.
• W1983353068 hasConcept C104317684 @default.
• W1983353068 hasConcept C133956753 @default.
• W1983353068 hasConcept C142354902 @default.
• W1983353068 hasConcept C153911025 @default.
• W1983353068 hasConcept C154472170 @default.
• W1983353068 hasConcept C181199279 @default.
• W1983353068 hasConcept C27253355 @default.
• W1983353068 hasConcept C2778305200 @default.
• W1983353068 hasConcept C2781098309 @default.
• W1983353068 hasConcept C2781264208 @default.
• W1983353068 hasConcept C2910677434 @default.
• W1983353068 hasConcept C45946802 @default.
• W1983353068 hasConcept C4951695 @default.
• W1983353068 hasConcept C54355233 @default.
• W1983353068 hasConcept C552990157 @default.
• W1983353068 hasConcept C55493867 @default.
• W1983353068 hasConcept C64927066 @default.
• W1983353068 hasConcept C71723506 @default.
• W1983353068 hasConcept C85240754 @default.
• W1983353068 hasConcept C86339819 @default.
• W1983353068 hasConcept C86803240 @default.
• W1983353068 hasConcept C95444343 @default.

• next