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- W1983394154 abstract "The kinetics of praziquantel was studied in normal and Schistosoma haematobium-infected Ghanaian subjects. There was a wide interindividual variation in half-life (t1/2), Cmax, Tmax, area under the curve (AUC) (0-8 h), and urinary recovery. No differences were noted between the two groups with regard to Tmax, AUC (0-8 h), and t1/2. Mean Cmax was higher in the patients than in the control subjects. The 8-hr urinary recovery of praziquantel was higher in the subjects with urinary schistosomiasis. The amount of praziquantel excreted unchanged in urine was 0.0052 +/- 0.0027% (SD) of the dose for the control subjects and 0.0054 +/- 0.0027% (SD) for the patients." @default.
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- W1983394154 date "1988-03-01" @default.
- W1983394154 modified "2023-09-25" @default.
- W1983394154 title "Oral Praziquantel Kinetics in Normal and Schistosoma haematobium-Infected Subjects" @default.
- W1983394154 doi "https://doi.org/10.1097/00007691-198801000-00008" @default.
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