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• W1983407559 abstract "RU486 is a very powerful antisteroid hormone compound, with antiprogestin and antiglucocorticosteroid clinical applications. High-affinity binding to the receptor ligand-binding domain results in essentially antagonistic function; however, some agonistlike effects have been observed. This review discusses the implications of recent discoveries concerning hsp90 (heat-shock protein M(r) approximately 90,000)-receptor interaction, receptor-DNA binding, and the involvement of transcription factors in the mechanism of action of RU486." @default.
• W1983407559 created "2016-06-24" @default.
• W1983407559 creator A5001677651 @default.
• W1983407559 date "1991-11-01" @default.
• W1983407559 modified "2023-10-18" @default.
• W1983407559 title "The antisteroid RU486 its cellular and molecular mode of action" @default.
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• W1983407559 doi "https://doi.org/10.1016/1043-2760(91)90030-q" @default.
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