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- W1983408048 abstract "Venous hypertension of the hand is an unusual complication of an arteriovenous shunt in patients receiving dialysis.We investigated whether in venous hypertension of the hand pericapillary cuffs are present and whether they consist of fibrin and other components.Biopsy specimens were taken from three patients with a side-to-side shunt and venous hypertension of the hand, from three patients with an end-to-side shunt without venous hypertension, and from three control subjects. The specimens were stained with antibodies against fibrinogen, fibrin, plasminogen activator inhibitor-I, factor VIII-related antigen, and collagen type IV.Pericapillary cuffs consisting of fibrin only were observed in patients with venous hypertension of the hand. In this fibrin network, factor VIII-related antigen and collagen type IV were also present. The finding of plasminogen activator inhibitor-I in the pericapillary cuff in the patient with the most severe signs of venous hypertension may indicate that breakdown of this fibrin cuff is impaired.Pericapillary cuffs may be of pathogenetic significance in venous hypertension of the hand." @default.
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- W1983408048 date "1994-07-01" @default.
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- W1983408048 title "Venous hypertension of the hand caused by hemodialysis shunt: Immunofluorescence studies of pericapillary cuffs" @default.
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- W1983408048 doi "https://doi.org/10.1016/s0190-9622(94)70129-6" @default.
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