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- W1983417259 abstract "Abstract The development of morphological changes in the stomach and small intestine of rats was observed for 75 days post infection (DPI) after oral infection with 1000 or 2000 eggs of Taenia taeniaeformis. Increases in size of both organs, due to mucosal hyperplasia, occurred earlier and tended to be more extreme in rats with the heaviest hepatic metacestode infections, although this was not always the case. Stomach weight increased up to 20-fold. Irregular proliferation of mucous epithelium and stroma of the lamina propria produced dramatic papillary and cystic thickening of the gastric mucosa with excessive mucus production. Weight and mucosal thickness of the small intestine doubled with little change in architecture or villus-crypt ratio of 2:1. Intestinal mast cell numbers increased throughout the observation period and were highest in the duodenum of heavily infected rats. In contrast, intestinal eosinophil numbers reached a peak between 30 and 40 DPI and then declined, in parallel with peripheral blood eosinophil counts. The implications of these gastrointestinal changes caused by a hepatic metacestode are discussed in terms of the possible mechanisms whereby they are produced and their significance in the host-parasite relationship." @default.
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- W1983417259 date "1981-04-01" @default.
- W1983417259 modified "2023-09-23" @default.
- W1983417259 title "Pathology of Taenia taeniaeformis infection in the rat: Gastrointestinal changes" @default.
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- W1983417259 doi "https://doi.org/10.1016/0021-9975(81)90025-6" @default.
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