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- W1983457976 abstract "Both receptor-mediated and diffusional processes have been proposed as mechanisms for the efflux of cellular cholesterol to plasma. The depletion of a minor high-density lipoprotein subfraction (pre beta-1-HDL) from plasma by incubation was associated with a proportional reduction in up to 58% of cholesterol and lecithin efflux from cultured fibroblasts. Pre beta-HDL-dependent efflux was blocked by protease pretreatment of the cells, while residual (nonspecific) efflux was protease-insensitive. The whole of cholesterol efflux from blood erythrocytes was both pre beta-1-HDL-and protease-independent. These data suggest that two distinct pathways contribute to total efflux from fibroblast monolayers; one of these is directly proportional to plasma pre beta-1-HDL concentration and may involve a cell-surface protein." @default.
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- W1983457976 date "1993-05-18" @default.
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- W1983457976 title "Quantitation of pre.beta.-HDL-dependent and nonspecific components of the total efflux of cellular cholesterol and phospholipid" @default.
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- W1983457976 doi "https://doi.org/10.1021/bi00070a008" @default.
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