FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983493392> ?p ?o ?g. }

• W1983493392 endingPage "169" @default.
• W1983493392 startingPage "164" @default.
• W1983493392 abstract "The aim of this study was to investigate the effect of erythropoietin on vascular contractility using an in vitro model of hypoxia replicating the hypoxic environment of blood vessels and surrounding adipose tissue in obesity.Pharmacological in vitro studies were carried out on small mesenteric arterial segments from male Wistar rats with and without perivascular fat and endothelium. Contractile responses were investigated by wire myography under normoxia, experimental hypoxia ± erythropoietin and l-NNA. Perivascular fat exerted an anticontractile effect which was lost following the induction of experimental hypoxia. Erythropoietin prevented the loss of the anticontractile capacity when vessels were incubated for one hour before the induction of hypoxia or throughout the period of hypoxia; this was found to be independent of the function of perivascular fat, as fat denuded arteries had a similar reduction in contractility (artery no fat + hypoxia vs. artery no fat + hypoxia + erythropoietin). The mechanism by which erythropoietin was exerting its effect was found to be partially endothelium dependent and associated with an increase of nitric oxide bioavailability as nitric oxide synthase inhibition prevented the effect.Whilst erythropoietin is working downstream from perivascular fat, it is possible that it may be therapeutically useful in obesity when hypoxia and inflammation reduce the normal activity of perivascular fat." @default.
• W1983493392 created "2016-06-24" @default.
• W1983493392 creator A5009257879 @default.
• W1983493392 creator A5013970531 @default.
• W1983493392 creator A5050182600 @default.
• W1983493392 creator A5061327404 @default.
• W1983493392 creator A5062835459 @default.
• W1983493392 date "2013-09-01" @default.
• W1983493392 modified "2023-09-26" @default.
• W1983493392 title "Erythropoietin has a restorative effect on the contractility of arteries following experimental hypoxia" @default.
• W1983493392 cites W1970445852 @default.
• W1983493392 cites W1980248069 @default.
• W1983493392 cites W1990521190 @default.
• W1983493392 cites W1993124089 @default.
• W1983493392 cites W2002945974 @default.
• W1983493392 cites W2005495277 @default.
• W1983493392 cites W2007157760 @default.
• W1983493392 cites W2029632724 @default.
• W1983493392 cites W2029738096 @default.
• W1983493392 cites W2037286582 @default.
• W1983493392 cites W2038008629 @default.
• W1983493392 cites W2039675151 @default.
• W1983493392 cites W2040242673 @default.
• W1983493392 cites W2051846093 @default.
• W1983493392 cites W2052109773 @default.
• W1983493392 cites W2059662266 @default.
• W1983493392 cites W2068462949 @default.
• W1983493392 cites W2076660967 @default.
• W1983493392 cites W2080760372 @default.
• W1983493392 cites W2083320249 @default.
• W1983493392 cites W2088369648 @default.
• W1983493392 cites W2093974904 @default.
• W1983493392 cites W2096890998 @default.
• W1983493392 cites W2100072314 @default.
• W1983493392 cites W2111691274 @default.
• W1983493392 cites W2115244899 @default.
• W1983493392 cites W2116041955 @default.
• W1983493392 cites W2119418002 @default.
• W1983493392 cites W2129637610 @default.
• W1983493392 cites W2141329138 @default.
• W1983493392 cites W2147604739 @default.
• W1983493392 cites W2148676557 @default.
• W1983493392 cites W2152809661 @default.
• W1983493392 cites W2153435592 @default.
• W1983493392 cites W2158634745 @default.
• W1983493392 cites W2160549233 @default.
• W1983493392 cites W2181431212 @default.
• W1983493392 cites W2916596946 @default.
• W1983493392 doi "https://doi.org/10.1016/j.jcdr.2013.08.002" @default.
• W1983493392 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3849290" @default.
• W1983493392 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24396255" @default.
• W1983493392 hasPublicationYear "2013" @default.
• W1983493392 type Work @default.
• W1983493392 sameAs 1983493392 @default.
• W1983493392 citedByCount "2" @default.
• W1983493392 countsByYear W19834933922015 @default.
• W1983493392 countsByYear W19834933922017 @default.
• W1983493392 crossrefType "journal-article" @default.
• W1983493392 hasAuthorship W1983493392A5009257879 @default.
• W1983493392 hasAuthorship W1983493392A5013970531 @default.
• W1983493392 hasAuthorship W1983493392A5050182600 @default.
• W1983493392 hasAuthorship W1983493392A5061327404 @default.
• W1983493392 hasAuthorship W1983493392A5062835459 @default.
• W1983493392 hasBestOaLocation W19834933922 @default.
• W1983493392 hasConcept C120770815 @default.
• W1983493392 hasConcept C126322002 @default.
• W1983493392 hasConcept C134018914 @default.
• W1983493392 hasConcept C171089720 @default.
• W1983493392 hasConcept C178790620 @default.
• W1983493392 hasConcept C185592680 @default.
• W1983493392 hasConcept C1918360 @default.
• W1983493392 hasConcept C2776820930 @default.
• W1983493392 hasConcept C2776992346 @default.
• W1983493392 hasConcept C2777622882 @default.
• W1983493392 hasConcept C2778534260 @default.
• W1983493392 hasConcept C2780771799 @default.
• W1983493392 hasConcept C39133596 @default.
• W1983493392 hasConcept C519581460 @default.
• W1983493392 hasConcept C540031477 @default.
• W1983493392 hasConcept C71924100 @default.
• W1983493392 hasConcept C7836513 @default.
• W1983493392 hasConceptScore W1983493392C120770815 @default.
• W1983493392 hasConceptScore W1983493392C126322002 @default.
• W1983493392 hasConceptScore W1983493392C134018914 @default.
• W1983493392 hasConceptScore W1983493392C171089720 @default.
• W1983493392 hasConceptScore W1983493392C178790620 @default.
• W1983493392 hasConceptScore W1983493392C185592680 @default.
• W1983493392 hasConceptScore W1983493392C1918360 @default.
• W1983493392 hasConceptScore W1983493392C2776820930 @default.
• W1983493392 hasConceptScore W1983493392C2776992346 @default.
• W1983493392 hasConceptScore W1983493392C2777622882 @default.
• W1983493392 hasConceptScore W1983493392C2778534260 @default.
• W1983493392 hasConceptScore W1983493392C2780771799 @default.
• W1983493392 hasConceptScore W1983493392C39133596 @default.
• W1983493392 hasConceptScore W1983493392C519581460 @default.
• W1983493392 hasConceptScore W1983493392C540031477 @default.
• W1983493392 hasConceptScore W1983493392C71924100 @default.
• W1983493392 hasConceptScore W1983493392C7836513 @default.

• next