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- W1983523284 abstract "In this report, the results of quantitative studies are given in support of our theory that by means of local pressor drug action on the superficial vessels of the dermis it is possible, in practice, to prevent the absorption of effective doses of a symptom-producing substance locally applied. The proposal to employ capillary constriction to certain new uses in surgery, as in the treatment of superficial burns, has been stated by me in a former report,<sup>1</sup>together with the application of the results obtained in the field of preventive medicine. Reports of other experimental studies and their clinical application will follow in this series. Sollmann and Pilcher<sup>2</sup>showed in 1916 that, when applied to<i>scarified</i>skin, epinephrin produces an area of blanching and goose-flesh. The injection of suprarenal extract along with procain, and similar substances to allay the rapid absorption of the latter, is a widely employed surgical" @default.
- W1983523284 created "2016-06-24" @default.
- W1983523284 creator A5084367018 @default.
- W1983523284 date "1924-02-02" @default.
- W1983523284 modified "2023-09-26" @default.
- W1983523284 title "RESTRICTION OF RATE OF FLOW AND INTERCHANGE IN CAPILLARIES BY VASOCONSTRICTOR DRUGS" @default.
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- W1983523284 doi "https://doi.org/10.1001/jama.1924.02650310035011" @default.
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