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• W1983530645 abstract "To investigate the expression level and clinical significance of microRNA-155 (miR-155) in bladder cancer.We collected 102 pairs of tissue specimens from patients with primary bladder cancer and adjacent normal bladder specimens between March 2008 and May 2013. Quantitative real-time polymerase chain reaction (QRT-PCR) was performed to detect the expression levels of miR-155. We performed univariate survival analyses using the Kaplan-Meier method and assessed statistical significance between survival curves via the log-rank test.The mean (SD) level of miR-155 expression in tissues with bladder cancer was 13.78 (4.80), which was significantly higher on average than that in adjacent normal bladder tissues (6.14 [2.26], P <.001). Progression-free survival (PFS) was significantly lower for patients with bladder cancer who had a high expression level of miR-155 (5-year survival rate, 23.0%) than those with a low miR-155 expression level (5-year survival rate, 48.9%; P <.001).We found that elevated expression of miR-155 is correlated with a poor outcome for patients with bladder cancer; this suggests that miR-155 is a potential biomarker for bladder cancer prognosis." @default.
• W1983530645 created "2016-06-24" @default.
• W1983530645 creator A5039892428 @default.
• W1983530645 creator A5057161101 @default.
• W1983530645 date "2015-05-01" @default.
• W1983530645 modified "2023-10-17" @default.
• W1983530645 title "Correlation of Increased Expression of MicroRNA-155 in Bladder Cancer and Prognosis" @default.
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• W1983530645 doi "https://doi.org/10.1309/lmwr9cea2k2xvsox" @default.
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