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• W1983537220 abstract "Abstract To evaluate whether there are age‐related differences in the characteristics of the circadian system in owl monkeys (Aotus lemurinus griseimembra) experiments analysing the resynchronization behaviour, the phase response to 3 h‐light pulses (LP), and the range of entrainment were carried out with 4 young (2–6 years), 5 middle‐aged (10–20 years), and 3 old (>20 years) animals. Following an 8 h‐delay shift of the entraining light‐dark cycle (LD 12:12; 100/230 lx : 0.2 lx) the monkeys’ locomotor activity rhythm re‐entrained significantly faster than after an 8 h‐advance shift. While no age‐associated differences in time needed for re‐entrainment (tr) could be detected following the delay‐shift, a difference appeared after the advance‐shift with faster re‐entrainment in the older animals. In a second experiment, the phase‐shifting effects of 3 h‐light pulses of 100 lx and 230 lx, respectively, applied at various phases of the circadian activity rhythm free‐running in constant dim light (LL) of 0.2 lx were tested. In all monkeys greater delay‐shifts than advance‐shifts could be elicited, but the phase response curve (PRC) constructed for the young animals showed a considerably smaller delay portion than that in old monkeys. For the period lengths of the free‐running rhythms no age‐related differences could be established. However, there was a more pronounced tendency to rhythm splitting in the young owl monkeys than in the old ones. The range of entrainment for LD‐cycles with 3 h light (100 lx) and 20–23 h darkness (0.2 lx) varied from ≤23 h (in 1 of 8 monkeys) to ≥26 h (in 3 of 8 monkeys). That it was often asymmetrically centered with regard to the individuals’ period length can be explained from of the shape of the PRC. Age‐related differences in the range of entrainment of the circadian activity rhythm were not found. Taken together the results seem to provide some evidence for a closer coupling of circadian oscillators in owl monkeys with increasing age. Abstracting keywords: Circadian rhythmagingre‐entrainmentphase‐responserange of entrainmentsplitting Aotus primates Notes Zoologisches Institut/Tierphysiologie der Universität Tübingen, Auf der Morgenstelle 28, D‐72076 Tübingen, Germany" @default.
• W1983537220 created "2016-06-24" @default.
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• W1983537220 date "1994-04-01" @default.
• W1983537220 modified "2023-10-18" @default.
• W1983537220 title "Re‐entrainment, phase‐response and range of entrainment of circadian rhythms in Owl Monkeys<i>(Aotus lemurinus g.)</i>of different age" @default.
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• W1983537220 doi "https://doi.org/10.1080/09291019409360282" @default.
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