Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983548257> ?p ?o ?g. }
- W1983548257 endingPage "321" @default.
- W1983548257 startingPage "316" @default.
- W1983548257 abstract "Epidermal stem cells (ESCs) are characterized as slowcycling, multi-potent, and self-renewing cells that not only maintain somatic homeostasis but also participate in tissue regeneration and repair. To examine the feasibility of adenoviral vector-mediated keratinocyte growth factor (KGF) gene transfer into in vitro-expanded ESCs, ESCs were isolated from samples of human skin, cultured in vitro, and then transfected with recombinant adenovirus (Ad) carrying the human KGF gene (AdKGF) or green fluorescent protein gene (AdGFP). The effects of KGF gene transfer on cell proliferation, cell cycle arrest, cell surface antigen phenotype, and β-catenin expression were investigated. Compared to ESCs transfected with AdGFP, AdKGFtransfected ESCs grew well, maintained a high proliferative capacity in keratinocyte serum-free medium, and expressed high levels of β-catenin. AdKGF infection increased the number of ESCs in the G0/G1 phase and promoted ESCs entry into the G2/M phase, but had no effect on cell surface antigen phenotype (CD49f+/CD71−). The results suggest that KGF gene transfer can stimulate ESCs to grow and undergo cell division, which can be applied to enhance cutaneous wound healing." @default.
- W1983548257 created "2016-06-24" @default.
- W1983548257 creator A5000797820 @default.
- W1983548257 creator A5018077554 @default.
- W1983548257 creator A5030843876 @default.
- W1983548257 creator A5035359720 @default.
- W1983548257 creator A5041598430 @default.
- W1983548257 creator A5046708618 @default.
- W1983548257 creator A5063205127 @default.
- W1983548257 creator A5071523575 @default.
- W1983548257 creator A5086833969 @default.
- W1983548257 date "2013-10-01" @default.
- W1983548257 modified "2023-09-26" @default.
- W1983548257 title "The effects of adenoviral transfection of the keratinocyte growth factor gene on epidermal stem cells: An in vitro study" @default.
- W1983548257 cites W1496601091 @default.
- W1983548257 cites W1789957686 @default.
- W1983548257 cites W1973697421 @default.
- W1983548257 cites W1978792905 @default.
- W1983548257 cites W1983836639 @default.
- W1983548257 cites W1985337907 @default.
- W1983548257 cites W1999829508 @default.
- W1983548257 cites W2002916416 @default.
- W1983548257 cites W2004736524 @default.
- W1983548257 cites W2011202983 @default.
- W1983548257 cites W2011842366 @default.
- W1983548257 cites W2012934896 @default.
- W1983548257 cites W2018791544 @default.
- W1983548257 cites W2022508905 @default.
- W1983548257 cites W2027380981 @default.
- W1983548257 cites W2030153375 @default.
- W1983548257 cites W2042850184 @default.
- W1983548257 cites W2046753298 @default.
- W1983548257 cites W2048686290 @default.
- W1983548257 cites W2052993929 @default.
- W1983548257 cites W2056294188 @default.
- W1983548257 cites W2065964498 @default.
- W1983548257 cites W2067591094 @default.
- W1983548257 cites W2079172185 @default.
- W1983548257 cites W2091841822 @default.
- W1983548257 cites W2095563608 @default.
- W1983548257 cites W2107277218 @default.
- W1983548257 cites W2121124983 @default.
- W1983548257 cites W2138295868 @default.
- W1983548257 cites W2142678690 @default.
- W1983548257 cites W2152708430 @default.
- W1983548257 cites W2164425162 @default.
- W1983548257 cites W2169671179 @default.
- W1983548257 doi "https://doi.org/10.1007/s10059-013-0093-y" @default.
- W1983548257 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3887989" @default.
- W1983548257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24170090" @default.
- W1983548257 hasPublicationYear "2013" @default.
- W1983548257 type Work @default.
- W1983548257 sameAs 1983548257 @default.
- W1983548257 citedByCount "5" @default.
- W1983548257 countsByYear W19835482572016 @default.
- W1983548257 countsByYear W19835482572017 @default.
- W1983548257 countsByYear W19835482572019 @default.
- W1983548257 countsByYear W19835482572023 @default.
- W1983548257 crossrefType "journal-article" @default.
- W1983548257 hasAuthorship W1983548257A5000797820 @default.
- W1983548257 hasAuthorship W1983548257A5018077554 @default.
- W1983548257 hasAuthorship W1983548257A5030843876 @default.
- W1983548257 hasAuthorship W1983548257A5035359720 @default.
- W1983548257 hasAuthorship W1983548257A5041598430 @default.
- W1983548257 hasAuthorship W1983548257A5046708618 @default.
- W1983548257 hasAuthorship W1983548257A5063205127 @default.
- W1983548257 hasAuthorship W1983548257A5071523575 @default.
- W1983548257 hasAuthorship W1983548257A5086833969 @default.
- W1983548257 hasBestOaLocation W19835482572 @default.
- W1983548257 hasConcept C104317684 @default.
- W1983548257 hasConcept C153911025 @default.
- W1983548257 hasConcept C170493617 @default.
- W1983548257 hasConcept C2775960820 @default.
- W1983548257 hasConcept C2777074287 @default.
- W1983548257 hasConcept C2778615670 @default.
- W1983548257 hasConcept C28328180 @default.
- W1983548257 hasConcept C32470452 @default.
- W1983548257 hasConcept C40767141 @default.
- W1983548257 hasConcept C54009773 @default.
- W1983548257 hasConcept C54355233 @default.
- W1983548257 hasConcept C81885089 @default.
- W1983548257 hasConcept C86803240 @default.
- W1983548257 hasConcept C95444343 @default.
- W1983548257 hasConceptScore W1983548257C104317684 @default.
- W1983548257 hasConceptScore W1983548257C153911025 @default.
- W1983548257 hasConceptScore W1983548257C170493617 @default.
- W1983548257 hasConceptScore W1983548257C2775960820 @default.
- W1983548257 hasConceptScore W1983548257C2777074287 @default.
- W1983548257 hasConceptScore W1983548257C2778615670 @default.
- W1983548257 hasConceptScore W1983548257C28328180 @default.
- W1983548257 hasConceptScore W1983548257C32470452 @default.
- W1983548257 hasConceptScore W1983548257C40767141 @default.
- W1983548257 hasConceptScore W1983548257C54009773 @default.
- W1983548257 hasConceptScore W1983548257C54355233 @default.
- W1983548257 hasConceptScore W1983548257C81885089 @default.
- W1983548257 hasConceptScore W1983548257C86803240 @default.
- W1983548257 hasConceptScore W1983548257C95444343 @default.
- W1983548257 hasIssue "4" @default.