FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983608532> ?p ?o ?g. }

• W1983608532 endingPage "2550" @default.
• W1983608532 startingPage "2543" @default.
• W1983608532 abstract "Background. The incidence and significance of tumor heterogeneity in primary tumors and metastatic lymph nodes were investigated in Stage IB–IIA cervical cancers. Methods. Paraffin-embedded tissues from 96 radical hysterectomy specimens were dewaxed, disaggregated, and subjected to dual parameter flow cytometry. Threedimensional histograms were generated to delineate different tumor populations. A DNA index difference of at least ± 0.15 was used to define tumor heterogeneity. Results. Mean DNA index difference of various tumor populations was 0.29 ± 0.13. Among 69 patients with normal lymph nodes, there were 12 patients (incidence, 17.4%) with tumor heterogeneity in the primary tumors. Of 27 patients with metastatic lymph nodes, 5 (incidence, 18.5%) had evidence of tumor heterogeneity in the primary tumor, and 18 of 47 (incidence, 38.3%) had tumor heterogeneity in metastatic lymph nodes. When using DNA index to determine clonal origin of metastatic lymph nodes, as many as 60% of the metastases could not be traced to the primary tumor. Tumor heterogeneity was associated with a 40% reduction in median survival time. However, because of the small number of patients with tumor heterogeneity, statistical analyses did not show prognostic significance. Conclusions. Tumor heterogeneity appeared to be a common characteristic of early cervical carcinoma. Additional study is needed to fully evaluate its prognostic value." @default.
• W1983608532 created "2016-06-24" @default.
• W1983608532 creator A5014830025 @default.
• W1983608532 creator A5025443583 @default.
• W1983608532 creator A5035042891 @default.
• W1983608532 creator A5057884900 @default.
• W1983608532 creator A5058542377 @default.
• W1983608532 creator A5074090550 @default.
• W1983608532 date "1993-04-15" @default.
• W1983608532 modified "2023-10-06" @default.
• W1983608532 title "Evidence of tumor heterogeneity in cervical cancers and lymph node metastases as determined by flow cytometry" @default.
• W1983608532 cites W1558416642 @default.
• W1983608532 cites W1969913007 @default.
• W1983608532 cites W1985413192 @default.
• W1983608532 cites W1998811052 @default.
• W1983608532 cites W2006556547 @default.
• W1983608532 cites W2011114833 @default.
• W1983608532 cites W2019931839 @default.
• W1983608532 cites W2021060316 @default.
• W1983608532 cites W2027159954 @default.
• W1983608532 cites W2037838633 @default.
• W1983608532 cites W2045154524 @default.
• W1983608532 cites W2047037282 @default.
• W1983608532 cites W2051521768 @default.
• W1983608532 cites W2055875132 @default.
• W1983608532 cites W2063462125 @default.
• W1983608532 cites W2066208520 @default.
• W1983608532 cites W2074053978 @default.
• W1983608532 cites W2074959117 @default.
• W1983608532 cites W2082452733 @default.
• W1983608532 cites W2093113003 @default.
• W1983608532 cites W2094734628 @default.
• W1983608532 cites W2415303375 @default.
• W1983608532 doi "https://doi.org/10.1002/1097-0142(19930415)71:8<2543::aid-cncr2820710818>3.0.co;2-u" @default.
• W1983608532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8453577" @default.
• W1983608532 hasPublicationYear "1993" @default.
• W1983608532 type Work @default.
• W1983608532 sameAs 1983608532 @default.
• W1983608532 citedByCount "15" @default.
• W1983608532 countsByYear W19836085322012 @default.
• W1983608532 countsByYear W19836085322015 @default.
• W1983608532 countsByYear W19836085322019 @default.
• W1983608532 crossrefType "journal-article" @default.
• W1983608532 hasAuthorship W1983608532A5014830025 @default.
• W1983608532 hasAuthorship W1983608532A5025443583 @default.
• W1983608532 hasAuthorship W1983608532A5035042891 @default.
• W1983608532 hasAuthorship W1983608532A5057884900 @default.
• W1983608532 hasAuthorship W1983608532A5058542377 @default.
• W1983608532 hasAuthorship W1983608532A5074090550 @default.
• W1983608532 hasBestOaLocation W19836085321 @default.
• W1983608532 hasConcept C120665830 @default.
• W1983608532 hasConcept C121332964 @default.
• W1983608532 hasConcept C121608353 @default.
• W1983608532 hasConcept C126322002 @default.
• W1983608532 hasConcept C142724271 @default.
• W1983608532 hasConcept C143998085 @default.
• W1983608532 hasConcept C146357865 @default.
• W1983608532 hasConcept C151730666 @default.
• W1983608532 hasConcept C203014093 @default.
• W1983608532 hasConcept C2778549279 @default.
• W1983608532 hasConcept C2779013556 @default.
• W1983608532 hasConcept C2779720271 @default.
• W1983608532 hasConcept C2780283643 @default.
• W1983608532 hasConcept C2780849966 @default.
• W1983608532 hasConcept C3018028425 @default.
• W1983608532 hasConcept C553184892 @default.
• W1983608532 hasConcept C61511704 @default.
• W1983608532 hasConcept C71924100 @default.
• W1983608532 hasConcept C86803240 @default.
• W1983608532 hasConceptScore W1983608532C120665830 @default.
• W1983608532 hasConceptScore W1983608532C121332964 @default.
• W1983608532 hasConceptScore W1983608532C121608353 @default.
• W1983608532 hasConceptScore W1983608532C126322002 @default.
• W1983608532 hasConceptScore W1983608532C142724271 @default.
• W1983608532 hasConceptScore W1983608532C143998085 @default.
• W1983608532 hasConceptScore W1983608532C146357865 @default.
• W1983608532 hasConceptScore W1983608532C151730666 @default.
• W1983608532 hasConceptScore W1983608532C203014093 @default.
• W1983608532 hasConceptScore W1983608532C2778549279 @default.
• W1983608532 hasConceptScore W1983608532C2779013556 @default.
• W1983608532 hasConceptScore W1983608532C2779720271 @default.
• W1983608532 hasConceptScore W1983608532C2780283643 @default.
• W1983608532 hasConceptScore W1983608532C2780849966 @default.
• W1983608532 hasConceptScore W1983608532C3018028425 @default.
• W1983608532 hasConceptScore W1983608532C553184892 @default.
• W1983608532 hasConceptScore W1983608532C61511704 @default.
• W1983608532 hasConceptScore W1983608532C71924100 @default.
• W1983608532 hasConceptScore W1983608532C86803240 @default.
• W1983608532 hasIssue "8" @default.
• W1983608532 hasLocation W19836085321 @default.
• W1983608532 hasLocation W19836085322 @default.
• W1983608532 hasOpenAccess W1983608532 @default.
• W1983608532 hasPrimaryLocation W19836085321 @default.
• W1983608532 hasRelatedWork W148651478 @default.
• W1983608532 hasRelatedWork W1983608532 @default.
• W1983608532 hasRelatedWork W2123141097 @default.
• W1983608532 hasRelatedWork W2408081278 @default.
• W1983608532 hasRelatedWork W2939546837 @default.

• next