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• W1983619321 startingPage "1034" @default.
• W1983619321 abstract "Abstract Intracellular uptake of nanoparticles is highly interesting for labeling of cells, drug delivery, or non‐viral gene delivery. In this study we have synthesized a wide variety of poly(alkyl methacrylate) nanoparticles with the same size and investigated their uptake into cells. The nanoparticles were prepared from alkylmethacrylates with different linear and branched ester chains as well as from benzylmethacrylate using the miniemulsion polymerizaiton technique. By adding a fluorescent dye as a marker, the internalization of the nanoparticles could be investigated quantitatively with flow cytometry and qualitatively with confocal laser scanning microscopy. With increasing side chain of the ester and therefore increasing hydrophobicity and at glass transition temperature ( T g ), below the incubation temperature of 37 °C the uptake of the nanoparticles into cells is favored. magnified image" @default.
• W1983619321 created "2016-06-24" @default.
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• W1983619321 date "2010-06-22" @default.
• W1983619321 modified "2023-10-18" @default.
• W1983619321 title "The Softer and More Hydrophobic the Better: Influence of the Side Chain of Polymethacrylate Nanoparticles for Cellular Uptake" @default.
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• W1983619321 doi "https://doi.org/10.1002/mabi.201000099" @default.
• W1983619321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20572275" @default.
• W1983619321 hasPublicationYear "2010" @default.
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