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- W1983642238 abstract "This study aimed at investigating if selective ex vivo immune deviation of myelin-specific cytokine secretion towards Th2 is possible in blood cells from patients with multiple sclerosis (MS). Interleukin (IL)-4 (Th2) and interferon-γ (Th1) secreting cells were recorded by ELISPOT in 13 MS patients. Deviation was successful in 10 patients. Interleukin-4 alone was most effective in inducing myelin-specific immune deviation in MS patients whereas IL-1 or IL-15 in combination with IL-4 did not improve the results. Further studies and improvements are needed before ex vivo immune deviation can be considered a potential treatment in patients with MS." @default.
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- W1983642238 date "2006-02-01" @default.
- W1983642238 modified "2023-09-24" @default.
- W1983642238 title "In vitro Th2 deviation of myelin-specific peripheral blood lymphocytes from patients with multiple sclerosis" @default.
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- W1983642238 doi "https://doi.org/10.1016/j.jneuroim.2005.09.013" @default.
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