FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983652511> ?p ?o ?g. }

• W1983652511 endingPage "650" @default.
• W1983652511 startingPage "643" @default.
• W1983652511 abstract "Groups of young adult, male rats were given free access for 12 weeks to a single diet containing either 12%, 24%, or 40% protein (dry weight). At the end of this time, six rats from each diet group were killed every four hours throughout a single 24-hour period, and blood samples and brains were obtained for quantitation of several of the large neutral amino acids (LNAAs). The blood level of each LNAA varied significantly as a function of time of day (tending to be lower during the day than at night) and as a function of dietary protein content (typically rising as protein intake increased). Except for tyrosine and valine, the serum concentration ratio of each LNAA to the sum of the other LNAA (previously reported to be a good predictor of the competitive uptake of each LNAA into brain) and the brain level of each LNAA showed unremarkable variations with time of day and dietary protein content. In contrast, the serum ratios and brain levels of tyrosine and valine did show notable variations at night as a function of dietary protein intake. Together, the results show that within a chronic physiologic range of protein intakes, the serum ratios and brain levels of several large neutral amino acids, particularly tryptophan, bear no relationship to dietary protein level. Though good correlations between these parameters and protein intake were obtained for valine and tyrosine, their physiologic/metabolic significance, if any, is unknown. In general, the data do not support the broad, unvalidated use of serum LNAA ratios in chronic settings as predictors of brain LNAA levels." @default.
• W1983652511 created "2016-06-24" @default.
• W1983652511 creator A5035209697 @default.
• W1983652511 creator A5035959132 @default.
• W1983652511 creator A5082110200 @default.
• W1983652511 date "1987-07-01" @default.
• W1983652511 modified "2023-10-15" @default.
• W1983652511 title "Twenty-four-hour variations in rat blood and brain levels of the aromatic and branched-chain amino acids: Chronic effects of dietary protein content" @default.
• W1983652511 cites W1557869684 @default.
• W1983652511 cites W1590347428 @default.
• W1983652511 cites W1750685322 @default.
• W1983652511 cites W1855176222 @default.
• W1983652511 cites W1942244377 @default.
• W1983652511 cites W1957381779 @default.
• W1983652511 cites W1967951232 @default.
• W1983652511 cites W1987778679 @default.
• W1983652511 cites W1988374896 @default.
• W1983652511 cites W1988511204 @default.
• W1983652511 cites W2005068370 @default.
• W1983652511 cites W2025444171 @default.
• W1983652511 cites W2056637478 @default.
• W1983652511 cites W2057084723 @default.
• W1983652511 cites W2068535052 @default.
• W1983652511 cites W2082325583 @default.
• W1983652511 cites W2083308861 @default.
• W1983652511 cites W2098323255 @default.
• W1983652511 cites W2124099730 @default.
• W1983652511 cites W2150399183 @default.
• W1983652511 cites W2264407089 @default.
• W1983652511 cites W4241761770 @default.
• W1983652511 cites W4383997435 @default.
• W1983652511 doi "https://doi.org/10.1016/0026-0495(87)90147-8" @default.
• W1983652511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3600278" @default.
• W1983652511 hasPublicationYear "1987" @default.
• W1983652511 type Work @default.
• W1983652511 sameAs 1983652511 @default.
• W1983652511 citedByCount "33" @default.
• W1983652511 countsByYear W19836525112012 @default.
• W1983652511 countsByYear W19836525112017 @default.
• W1983652511 countsByYear W19836525112022 @default.
• W1983652511 countsByYear W19836525112023 @default.
• W1983652511 crossrefType "journal-article" @default.
• W1983652511 hasAuthorship W1983652511A5035209697 @default.
• W1983652511 hasAuthorship W1983652511A5035959132 @default.
• W1983652511 hasAuthorship W1983652511A5082110200 @default.
• W1983652511 hasConcept C126322002 @default.
• W1983652511 hasConcept C134018914 @default.
• W1983652511 hasConcept C140793950 @default.
• W1983652511 hasConcept C185592680 @default.
• W1983652511 hasConcept C2776165026 @default.
• W1983652511 hasConcept C2776706248 @default.
• W1983652511 hasConcept C2777573094 @default.
• W1983652511 hasConcept C515207424 @default.
• W1983652511 hasConcept C55493867 @default.
• W1983652511 hasConcept C71924100 @default.
• W1983652511 hasConcept C86803240 @default.
• W1983652511 hasConceptScore W1983652511C126322002 @default.
• W1983652511 hasConceptScore W1983652511C134018914 @default.
• W1983652511 hasConceptScore W1983652511C140793950 @default.
• W1983652511 hasConceptScore W1983652511C185592680 @default.
• W1983652511 hasConceptScore W1983652511C2776165026 @default.
• W1983652511 hasConceptScore W1983652511C2776706248 @default.
• W1983652511 hasConceptScore W1983652511C2777573094 @default.
• W1983652511 hasConceptScore W1983652511C515207424 @default.
• W1983652511 hasConceptScore W1983652511C55493867 @default.
• W1983652511 hasConceptScore W1983652511C71924100 @default.
• W1983652511 hasConceptScore W1983652511C86803240 @default.
• W1983652511 hasIssue "7" @default.
• W1983652511 hasLocation W19836525111 @default.
• W1983652511 hasLocation W19836525112 @default.
• W1983652511 hasOpenAccess W1983652511 @default.
• W1983652511 hasPrimaryLocation W19836525111 @default.
• W1983652511 hasRelatedWork W138405781 @default.
• W1983652511 hasRelatedWork W1762520686 @default.
• W1983652511 hasRelatedWork W1983354615 @default.
• W1983652511 hasRelatedWork W1993575366 @default.
• W1983652511 hasRelatedWork W2004046901 @default.
• W1983652511 hasRelatedWork W2078780432 @default.
• W1983652511 hasRelatedWork W2079291036 @default.
• W1983652511 hasRelatedWork W2108922026 @default.
• W1983652511 hasRelatedWork W2130962793 @default.
• W1983652511 hasRelatedWork W250662556 @default.
• W1983652511 hasVolume "36" @default.
• W1983652511 isParatext "false" @default.
• W1983652511 isRetracted "false" @default.
• W1983652511 magId "1983652511" @default.
• W1983652511 workType "article" @default.