FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983655116> ?p ?o ?g. }

• W1983655116 endingPage "7" @default.
• W1983655116 startingPage "1" @default.
• W1983655116 abstract "Long noncoding RNAs (lncRNAs) are emerging as key regulators of diverse cell functions and processes. However, the relevance of lncRNAs in the cell and tissue response to ionizing radiation has not yet been characterized. Here we used microarray profiling to determine lncRNA and mRNA expression in mammary glands of BALB/c and SPRET/EiJ mice after low-dose ionizing radiation (LDIR) exposure. We found that unirradiated mammary tissues of these strains differed significantly in baseline expressions of 290 lncRNAs. LDIR exposure (10 cGy) induced a significant change in the expression of many lncRNAs. The vast majority of lncRNAs identified to be differentially expressed after LDIR in either BALB/c or SPRET/EiJ had a significantly correlated expression pattern with at least one LDIR responsive mRNA. Functional analysis revealed that the response to LDIR in BALB/c mice is highly dynamic with enrichment for genes involved in tissue injury, inflammatory responses, and mammary gland development at 2, 4, and 8 weeks after LDIR, respectively. Our study demonstrates that genetic background strongly influences the expression of lncRNAs and their response to radiation and that lncRNAs may coordinate the tissue response to LDIR exposure via regulation of coding mRNAs." @default.
• W1983655116 created "2016-06-24" @default.
• W1983655116 creator A5007659827 @default.
• W1983655116 creator A5032768695 @default.
• W1983655116 creator A5039340406 @default.
• W1983655116 creator A5061738677 @default.
• W1983655116 creator A5076358770 @default.
• W1983655116 creator A5088743448 @default.
• W1983655116 date "2015-01-01" @default.
• W1983655116 modified "2023-09-27" @default.
• W1983655116 title "Genetic Background Modulates lncRNA-Coordinated Tissue Response to Low Dose Ionizing Radiation" @default.
• W1983655116 cites W1811444095 @default.
• W1983655116 cites W1997600268 @default.
• W1983655116 cites W2003723466 @default.
• W1983655116 cites W2010712786 @default.
• W1983655116 cites W2024762854 @default.
• W1983655116 cites W2024846717 @default.
• W1983655116 cites W2027239369 @default.
• W1983655116 cites W2031573318 @default.
• W1983655116 cites W2032183472 @default.
• W1983655116 cites W2078988557 @default.
• W1983655116 cites W2096531284 @default.
• W1983655116 cites W2097155520 @default.
• W1983655116 cites W2104469528 @default.
• W1983655116 cites W2105292164 @default.
• W1983655116 cites W2110496314 @default.
• W1983655116 cites W2112343036 @default.
• W1983655116 cites W2120187508 @default.
• W1983655116 cites W2144209063 @default.
• W1983655116 cites W2159012899 @default.
• W1983655116 cites W2167714537 @default.
• W1983655116 cites W2181989274 @default.
• W1983655116 doi "https://doi.org/10.1155/2015/461038" @default.
• W1983655116 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4353441" @default.
• W1983655116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25802832" @default.
• W1983655116 hasPublicationYear "2015" @default.
• W1983655116 type Work @default.
• W1983655116 sameAs 1983655116 @default.
• W1983655116 citedByCount "4" @default.
• W1983655116 countsByYear W19836551162018 @default.
• W1983655116 countsByYear W19836551162020 @default.
• W1983655116 countsByYear W19836551162022 @default.
• W1983655116 crossrefType "journal-article" @default.
• W1983655116 hasAuthorship W1983655116A5007659827 @default.
• W1983655116 hasAuthorship W1983655116A5032768695 @default.
• W1983655116 hasAuthorship W1983655116A5039340406 @default.
• W1983655116 hasAuthorship W1983655116A5061738677 @default.
• W1983655116 hasAuthorship W1983655116A5076358770 @default.
• W1983655116 hasAuthorship W1983655116A5088743448 @default.
• W1983655116 hasBestOaLocation W19836551161 @default.
• W1983655116 hasConcept C104317684 @default.
• W1983655116 hasConcept C105580179 @default.
• W1983655116 hasConcept C111337013 @default.
• W1983655116 hasConcept C121332964 @default.
• W1983655116 hasConcept C150194340 @default.
• W1983655116 hasConcept C153911025 @default.
• W1983655116 hasConcept C18231593 @default.
• W1983655116 hasConcept C18431079 @default.
• W1983655116 hasConcept C185544564 @default.
• W1983655116 hasConcept C186836561 @default.
• W1983655116 hasConcept C2781369401 @default.
• W1983655116 hasConcept C502942594 @default.
• W1983655116 hasConcept C54355233 @default.
• W1983655116 hasConcept C62203573 @default.
• W1983655116 hasConcept C67705224 @default.
• W1983655116 hasConcept C8415881 @default.
• W1983655116 hasConcept C86803240 @default.
• W1983655116 hasConceptScore W1983655116C104317684 @default.
• W1983655116 hasConceptScore W1983655116C105580179 @default.
• W1983655116 hasConceptScore W1983655116C111337013 @default.
• W1983655116 hasConceptScore W1983655116C121332964 @default.
• W1983655116 hasConceptScore W1983655116C150194340 @default.
• W1983655116 hasConceptScore W1983655116C153911025 @default.
• W1983655116 hasConceptScore W1983655116C18231593 @default.
• W1983655116 hasConceptScore W1983655116C18431079 @default.
• W1983655116 hasConceptScore W1983655116C185544564 @default.
• W1983655116 hasConceptScore W1983655116C186836561 @default.
• W1983655116 hasConceptScore W1983655116C2781369401 @default.
• W1983655116 hasConceptScore W1983655116C502942594 @default.
• W1983655116 hasConceptScore W1983655116C54355233 @default.
• W1983655116 hasConceptScore W1983655116C62203573 @default.
• W1983655116 hasConceptScore W1983655116C67705224 @default.
• W1983655116 hasConceptScore W1983655116C8415881 @default.
• W1983655116 hasConceptScore W1983655116C86803240 @default.
• W1983655116 hasFunder F4320306084 @default.
• W1983655116 hasLocation W19836551161 @default.
• W1983655116 hasLocation W19836551162 @default.
• W1983655116 hasLocation W19836551163 @default.
• W1983655116 hasLocation W19836551164 @default.
• W1983655116 hasLocation W19836551165 @default.
• W1983655116 hasLocation W19836551166 @default.
• W1983655116 hasLocation W19836551167 @default.
• W1983655116 hasLocation W19836551168 @default.
• W1983655116 hasLocation W19836551169 @default.
• W1983655116 hasOpenAccess W1983655116 @default.
• W1983655116 hasPrimaryLocation W19836551161 @default.
• W1983655116 hasRelatedWork W1531528770 @default.
• W1983655116 hasRelatedWork W1983994322 @default.

• next