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- W1983668232 abstract "The role of Sonic hedgehog (Shh) as a morphogen in diverse developmental settings depends on covalent addition of cholesterol. In this study, expression of Shh lacking cholesterol stimulated hair growth with greater efficacy than native Shh, suggesting that Shh acts as a chemokine rather than a morphogen in this postnatal role. Thus, a structural modification that renders a morphogen ineffective in developmental models may have distinct advantages for postnatal applications." @default.
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- W1983668232 date "2005-09-01" @default.
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- W1983668232 title "Enhanced Efficacy of Cholesterol-Minus Sonic Hedgehog in Postnatal Skin" @default.
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- W1983668232 doi "https://doi.org/10.1016/j.ymthe.2005.01.009" @default.
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