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• W1983706844 startingPage "219" @default.
• W1983706844 abstract "Large numbers of human infants are exposed in utero to illicit opiate drugs such as heroin and to prescribed opiates such as methadone. It is therefore important to understand the effects of acute and chronic exposure to drugs such as these on the immature organism. A necessary step in understanding the long-term effects of early drug exposure is to describe fully how the drug acts on neurobehavioral systems in the neonate. Because infants typically experience withdrawal from opiates, either in utero or shortly after parturition, a fuller understanding of the consequences of opiate withdrawal in the immature animal is an important but largely unexplored area of research. Although there has been some question as to whether infants undergo withdrawal, more recent experiments demonstrate that the rat neonate experiences clear behavioral changes during opiate abstinence, including the induction of dysphoric states on cessation of drug exposure. It is proposed that the infant organism undergoes withdrawal but that the signs and symptoms experienced differ from those suffered by the adult." @default.
• W1983706844 created "2016-06-24" @default.
• W1983706844 creator A5013219765 @default.
• W1983706844 creator A5019208350 @default.
• W1983706844 date "1994-03-01" @default.
• W1983706844 modified "2023-10-16" @default.
• W1983706844 title "Opiate withdrawal in the infant" @default.
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• W1983706844 doi "https://doi.org/10.1016/0892-0362(94)90121-x" @default.
• W1983706844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8052197" @default.
• W1983706844 hasPublicationYear "1994" @default.
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