FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983709382> ?p ?o ?g. }

• W1983709382 endingPage "917" @default.
• W1983709382 startingPage "907" @default.
• W1983709382 abstract "Reactive oxygen species (ROS)/reactive nitrogen species (RNS) and ROS/RNS-mediated oxidative stress have well-established roles in many physiological and pathological processes and are associated with the pathogenesis of many diseases, such as hypertension, ischemia/reperfusion injury, diabetes mellitus, atherosclerosis, stroke, cancer, and neurodegenerative disorders. It is generally accepted that mitochondria play an essential role in oxidative stress because they are responsible for the primary generation of superoxide radicals. Little attention, however, has been paid to the importance of the Golgi apparatus (GA) in this process. The GA is a pivotal organelle in cell metabolism and participates in modifying, sorting, and packaging macromolecules for cell secretion or use within the cell. It is inevitably involved in the process of oxidative stress, which can cause modification and damage of lipids, proteins, DNA, and other structural constituents. Here we discuss the connections between the GA and oxidative stress and highlight the role of the GA in oxidative stress-related Ca2+/Mn2+ homeostasis, cell apoptosis, sphingolipid metabolism, signal transduction, and antioxidation. We also provide a novel perspective on the subcellular significance of oxidative stress and its pathological implications and present “GA stress” as a new concept to explain the GA-specific stress response." @default.
• W1983709382 created "2016-06-24" @default.
• W1983709382 creator A5012116287 @default.
• W1983709382 creator A5013242926 @default.
• W1983709382 creator A5031818289 @default.
• W1983709382 creator A5035267870 @default.
• W1983709382 creator A5049115038 @default.
• W1983709382 creator A5061817335 @default.
• W1983709382 creator A5066907634 @default.
• W1983709382 date "2011-04-01" @default.
• W1983709382 modified "2023-10-01" @default.
• W1983709382 title "The role of the Golgi apparatus in oxidative stress: is this organelle less significant than mitochondria?" @default.
• W1983709382 cites W102919716 @default.
• W1983709382 cites W1507318381 @default.
• W1983709382 cites W1518225155 @default.
• W1983709382 cites W1522763255 @default.
• W1983709382 cites W1525010478 @default.
• W1983709382 cites W1533165142 @default.
• W1983709382 cites W1597695775 @default.
• W1983709382 cites W1608856014 @default.
• W1983709382 cites W1693383484 @default.
• W1983709382 cites W1784820495 @default.
• W1983709382 cites W181801780 @default.
• W1983709382 cites W1823494905 @default.
• W1983709382 cites W1839658873 @default.
• W1983709382 cites W1905806846 @default.
• W1983709382 cites W1935962442 @default.
• W1983709382 cites W1965316807 @default.
• W1983709382 cites W1971758358 @default.
• W1983709382 cites W1974062392 @default.
• W1983709382 cites W1974954009 @default.
• W1983709382 cites W1975130127 @default.
• W1983709382 cites W1976812939 @default.
• W1983709382 cites W1977069725 @default.
• W1983709382 cites W1977913875 @default.
• W1983709382 cites W1978911202 @default.
• W1983709382 cites W1979713533 @default.
• W1983709382 cites W1981360487 @default.
• W1983709382 cites W1984142578 @default.
• W1983709382 cites W1984873106 @default.
• W1983709382 cites W1986048086 @default.
• W1983709382 cites W1987102030 @default.
• W1983709382 cites W1987180083 @default.
• W1983709382 cites W1991628735 @default.
• W1983709382 cites W1992586088 @default.
• W1983709382 cites W1994104851 @default.
• W1983709382 cites W1994132984 @default.
• W1983709382 cites W1995791222 @default.
• W1983709382 cites W1997411677 @default.
• W1983709382 cites W1997895489 @default.
• W1983709382 cites W1998923026 @default.
• W1983709382 cites W1999312453 @default.
• W1983709382 cites W2000137674 @default.
• W1983709382 cites W2000823512 @default.
• W1983709382 cites W2000998571 @default.
• W1983709382 cites W2001565942 @default.
• W1983709382 cites W2001956269 @default.
• W1983709382 cites W2004686044 @default.
• W1983709382 cites W2005545438 @default.
• W1983709382 cites W2006388911 @default.
• W1983709382 cites W2007459574 @default.
• W1983709382 cites W2007835830 @default.
• W1983709382 cites W2011342890 @default.
• W1983709382 cites W2013135033 @default.
• W1983709382 cites W2013624095 @default.
• W1983709382 cites W2014091183 @default.
• W1983709382 cites W2014100516 @default.
• W1983709382 cites W2015965270 @default.
• W1983709382 cites W2019256890 @default.
• W1983709382 cites W2021745031 @default.
• W1983709382 cites W2022153221 @default.
• W1983709382 cites W2022456060 @default.
• W1983709382 cites W2024193478 @default.
• W1983709382 cites W2024724647 @default.
• W1983709382 cites W2026495582 @default.
• W1983709382 cites W2026756449 @default.
• W1983709382 cites W2027048243 @default.
• W1983709382 cites W2028075356 @default.
• W1983709382 cites W2029000167 @default.
• W1983709382 cites W2030540514 @default.
• W1983709382 cites W2033302141 @default.
• W1983709382 cites W2033433699 @default.
• W1983709382 cites W2034644844 @default.
• W1983709382 cites W2034862605 @default.
• W1983709382 cites W2035162752 @default.
• W1983709382 cites W2037334479 @default.
• W1983709382 cites W2039444414 @default.
• W1983709382 cites W2040538522 @default.
• W1983709382 cites W2041191443 @default.
• W1983709382 cites W2041343852 @default.
• W1983709382 cites W2041805545 @default.
• W1983709382 cites W2041896590 @default.
• W1983709382 cites W2043721012 @default.
• W1983709382 cites W2045785885 @default.
• W1983709382 cites W2046456449 @default.
• W1983709382 cites W2047932097 @default.
• W1983709382 cites W2053022803 @default.
• W1983709382 cites W2053548069 @default.

• next