FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983724220> ?p ?o ?g. }

• W1983724220 endingPage "173" @default.
• W1983724220 startingPage "163" @default.
• W1983724220 abstract "The inferior colliculus (IC) is an important auditory processing center receiving inputs from lower brainstem nuclei, higher auditory and nonauditory structures, and contralateral IC. The IC, along with other auditory structures, is involved in coding information about the envelope of complex signals. Biologically relevant acoustic signals, including animal vocalizations and speech, are spectrally and temporally complex and display amplitude and frequency variations over time. Certain IC neurons respond selectively over a narrow range of modulation frequencies to sinusoidally amplitude modulated (SAM) stimuli. Responses to SAM stimuli can be measured in terms of discharge rate, with rate plotted against the modulation frequency to generate rate modulation transfer functions (rMTF). A role for the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), in shaping selective responses to SAM stimuli has been suggested. The present study examined the role of GABA in shaping responses to SAM stimuli in the IC of anesthetized chinchilla. Responses from 94 IC neurons were obtained before, during and after iontophoretic application of the GABAA receptor antagonist bicuculline methiodide. Complete responses to SAM stimuli were obtained from 55 extensively tested neurons, displaying band-pass (38) and low-pass rMTFs (17). For neurons showing band-pass rMTFs, GABAA receptor blockade selectively increased discharge rate at low modulation frequencies for 14 units, increased discharge near the best modulation frequency for 12 units. For neurons showing low-pass rMTFs, GABAA receptor blockade selectively increased discharge rate at low modulation frequencies for nine units. GABAA receptor blockade consistently reduced peak modulation gain, producing low-pass gain functions in a subset of IC neurons. In support of previous findings suggesting that selective temporal responses to SAM stimuli are coded in lower brainstem nuclei, temporal responses to SAM stimuli were relatively unaffected by GABAA receptor blockade. These findings support a role for GABA in shaping selective rate responses to SAM stimuli for a subset of chinchilla IC neurons." @default.
• W1983724220 created "2016-06-24" @default.
• W1983724220 creator A5071163440 @default.
• W1983724220 creator A5085891818 @default.
• W1983724220 creator A5091054081 @default.
• W1983724220 date "2002-06-01" @default.
• W1983724220 modified "2023-10-16" @default.
• W1983724220 title "GABAergic inputs shape responses to amplitude modulated stimuli in the inferior colliculus" @default.
• W1983724220 cites W1256152654 @default.
• W1983724220 cites W135189209 @default.
• W1983724220 cites W1511612315 @default.
• W1983724220 cites W1532998256 @default.
• W1983724220 cites W1591075818 @default.
• W1983724220 cites W164832740 @default.
• W1983724220 cites W1908388707 @default.
• W1983724220 cites W1928080722 @default.
• W1983724220 cites W1964393624 @default.
• W1983724220 cites W1969011695 @default.
• W1983724220 cites W1971768496 @default.
• W1983724220 cites W1973265140 @default.
• W1983724220 cites W1973771822 @default.
• W1983724220 cites W1983700943 @default.
• W1983724220 cites W1991167146 @default.
• W1983724220 cites W1992890284 @default.
• W1983724220 cites W199530321 @default.
• W1983724220 cites W2008705869 @default.
• W1983724220 cites W2011082008 @default.
• W1983724220 cites W2012958850 @default.
• W1983724220 cites W2014316007 @default.
• W1983724220 cites W2019499799 @default.
• W1983724220 cites W2026049607 @default.
• W1983724220 cites W2027594633 @default.
• W1983724220 cites W2028502900 @default.
• W1983724220 cites W2030160825 @default.
• W1983724220 cites W2033092808 @default.
• W1983724220 cites W2036110480 @default.
• W1983724220 cites W2036931979 @default.
• W1983724220 cites W2038011949 @default.
• W1983724220 cites W2039029732 @default.
• W1983724220 cites W2045399727 @default.
• W1983724220 cites W2046408582 @default.
• W1983724220 cites W2050789905 @default.
• W1983724220 cites W2051895501 @default.
• W1983724220 cites W2060474838 @default.
• W1983724220 cites W2061831963 @default.
• W1983724220 cites W2067358098 @default.
• W1983724220 cites W2072642646 @default.
• W1983724220 cites W2072906760 @default.
• W1983724220 cites W2081413612 @default.
• W1983724220 cites W2091247836 @default.
• W1983724220 cites W2091995255 @default.
• W1983724220 cites W2095428663 @default.
• W1983724220 cites W2114089489 @default.
• W1983724220 cites W2129857634 @default.
• W1983724220 cites W2134381549 @default.
• W1983724220 cites W2149261736 @default.
• W1983724220 cites W2154382930 @default.
• W1983724220 cites W2159149636 @default.
• W1983724220 cites W2179094064 @default.
• W1983724220 cites W2235346210 @default.
• W1983724220 cites W2332516414 @default.
• W1983724220 cites W2405043670 @default.
• W1983724220 cites W2412241062 @default.
• W1983724220 cites W2415384423 @default.
• W1983724220 cites W2415996078 @default.
• W1983724220 cites W4301289262 @default.
• W1983724220 doi "https://doi.org/10.1016/s0378-5955(02)00363-5" @default.
• W1983724220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12117518" @default.
• W1983724220 hasPublicationYear "2002" @default.
• W1983724220 type Work @default.
• W1983724220 sameAs 1983724220 @default.
• W1983724220 citedByCount "98" @default.
• W1983724220 countsByYear W19837242202012 @default.
• W1983724220 countsByYear W19837242202013 @default.
• W1983724220 countsByYear W19837242202014 @default.
• W1983724220 countsByYear W19837242202015 @default.
• W1983724220 countsByYear W19837242202016 @default.
• W1983724220 countsByYear W19837242202017 @default.
• W1983724220 countsByYear W19837242202018 @default.
• W1983724220 countsByYear W19837242202019 @default.
• W1983724220 countsByYear W19837242202020 @default.
• W1983724220 countsByYear W19837242202021 @default.
• W1983724220 countsByYear W19837242202022 @default.
• W1983724220 crossrefType "journal-article" @default.
• W1983724220 hasAuthorship W1983724220A5071163440 @default.
• W1983724220 hasAuthorship W1983724220A5085891818 @default.
• W1983724220 hasAuthorship W1983724220A5091054081 @default.
• W1983724220 hasConcept C168258287 @default.
• W1983724220 hasConcept C169760540 @default.
• W1983724220 hasConcept C170493617 @default.
• W1983724220 hasConcept C17077164 @default.
• W1983724220 hasConcept C185263204 @default.
• W1983724220 hasConcept C185592680 @default.
• W1983724220 hasConcept C2775980177 @default.
• W1983724220 hasConcept C2780723820 @default.
• W1983724220 hasConcept C2780763569 @default.
• W1983724220 hasConcept C55493867 @default.
• W1983724220 hasConcept C86803240 @default.

• next