Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983761330> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1983761330 endingPage "85" @default.
- W1983761330 startingPage "73" @default.
- W1983761330 abstract "Our experiments with transfected cells provide new insights into the role of Na-Ca exchange activity in Ca homeostasis and emphasize the role of local interactions in determining exchanger function. Thus, the effects of ATP depletion and cytochalasin D highlight the influence of the actin cytoskeleton in regulating exchange activity. Cytoskeletal interactions could provide a mechanism for modulating exchange activity by mechanical stretch and might constitute a novel feedback mechanism for regulating contractile activity in the heart. The effects of Na on Ca entry during SDCI in the transfected cells suggest that local gradients of [Ca]i are important determinants of exchanger function. The surface distribution of exchanger proteins in relation to that of Ca channels therefore represents another area in which interactions with the cytoskeleton may be a central element in understanding the physiological function(s) of the exchange activity. At present, it seems likely that the exchanger's central hydrophilic domain mediates the connection between the exchanger and the cytoskeleton. This provides a rationale for understanding the importance of tissue-specific alterations in the exchanger's hydrophilic domain, which appear to have little affect on the kinetic behavior of the exchanger. Future work in our laboratory will be directed toward clarifying the role of cytoskeletal interactions in exchanger function." @default.
- W1983761330 created "2016-06-24" @default.
- W1983761330 creator A5007098708 @default.
- W1983761330 creator A5032767292 @default.
- W1983761330 creator A5036375618 @default.
- W1983761330 date "1996-04-01" @default.
- W1983761330 modified "2023-09-23" @default.
- W1983761330 title "Sodium-Calcium Exchange and Calcium Homeostasis in Transfected Chinese Hamster Ovary Cellsa" @default.
- W1983761330 cites W145796029 @default.
- W1983761330 cites W1492909811 @default.
- W1983761330 cites W1518461235 @default.
- W1983761330 cites W1600304302 @default.
- W1983761330 cites W1795554797 @default.
- W1983761330 cites W1936649411 @default.
- W1983761330 cites W1987476658 @default.
- W1983761330 cites W1991220984 @default.
- W1983761330 cites W2009601122 @default.
- W1983761330 cites W2010894303 @default.
- W1983761330 cites W2020582031 @default.
- W1983761330 cites W2041562159 @default.
- W1983761330 cites W2043883936 @default.
- W1983761330 cites W2045546690 @default.
- W1983761330 cites W2060053293 @default.
- W1983761330 cites W2081926380 @default.
- W1983761330 cites W2082208569 @default.
- W1983761330 cites W2097858715 @default.
- W1983761330 cites W2099654084 @default.
- W1983761330 cites W2109449392 @default.
- W1983761330 cites W2114827440 @default.
- W1983761330 cites W2128270335 @default.
- W1983761330 cites W2468889660 @default.
- W1983761330 cites W2472988102 @default.
- W1983761330 cites W304878669 @default.
- W1983761330 doi "https://doi.org/10.1111/j.1749-6632.1996.tb44771.x" @default.
- W1983761330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8659883" @default.
- W1983761330 hasPublicationYear "1996" @default.
- W1983761330 type Work @default.
- W1983761330 sameAs 1983761330 @default.
- W1983761330 citedByCount "5" @default.
- W1983761330 crossrefType "journal-article" @default.
- W1983761330 hasAuthorship W1983761330A5007098708 @default.
- W1983761330 hasAuthorship W1983761330A5032767292 @default.
- W1983761330 hasAuthorship W1983761330A5036375618 @default.
- W1983761330 hasConcept C104317684 @default.
- W1983761330 hasConcept C12554922 @default.
- W1983761330 hasConcept C142669718 @default.
- W1983761330 hasConcept C1491633281 @default.
- W1983761330 hasConcept C170493617 @default.
- W1983761330 hasConcept C175656101 @default.
- W1983761330 hasConcept C178790620 @default.
- W1983761330 hasConcept C185592680 @default.
- W1983761330 hasConcept C2775995422 @default.
- W1983761330 hasConcept C2777735026 @default.
- W1983761330 hasConcept C2993400109 @default.
- W1983761330 hasConcept C519063684 @default.
- W1983761330 hasConcept C54009773 @default.
- W1983761330 hasConcept C55493867 @default.
- W1983761330 hasConcept C79879829 @default.
- W1983761330 hasConcept C86803240 @default.
- W1983761330 hasConcept C95444343 @default.
- W1983761330 hasConceptScore W1983761330C104317684 @default.
- W1983761330 hasConceptScore W1983761330C12554922 @default.
- W1983761330 hasConceptScore W1983761330C142669718 @default.
- W1983761330 hasConceptScore W1983761330C1491633281 @default.
- W1983761330 hasConceptScore W1983761330C170493617 @default.
- W1983761330 hasConceptScore W1983761330C175656101 @default.
- W1983761330 hasConceptScore W1983761330C178790620 @default.
- W1983761330 hasConceptScore W1983761330C185592680 @default.
- W1983761330 hasConceptScore W1983761330C2775995422 @default.
- W1983761330 hasConceptScore W1983761330C2777735026 @default.
- W1983761330 hasConceptScore W1983761330C2993400109 @default.
- W1983761330 hasConceptScore W1983761330C519063684 @default.
- W1983761330 hasConceptScore W1983761330C54009773 @default.
- W1983761330 hasConceptScore W1983761330C55493867 @default.
- W1983761330 hasConceptScore W1983761330C79879829 @default.
- W1983761330 hasConceptScore W1983761330C86803240 @default.
- W1983761330 hasConceptScore W1983761330C95444343 @default.
- W1983761330 hasIssue "1" @default.
- W1983761330 hasLocation W19837613301 @default.
- W1983761330 hasLocation W19837613302 @default.
- W1983761330 hasOpenAccess W1983761330 @default.
- W1983761330 hasPrimaryLocation W19837613301 @default.
- W1983761330 hasRelatedWork W131757845 @default.
- W1983761330 hasRelatedWork W1971634319 @default.
- W1983761330 hasRelatedWork W1983761330 @default.
- W1983761330 hasRelatedWork W2018466181 @default.
- W1983761330 hasRelatedWork W2113266085 @default.
- W1983761330 hasRelatedWork W2141715168 @default.
- W1983761330 hasRelatedWork W2158044026 @default.
- W1983761330 hasRelatedWork W2594707584 @default.
- W1983761330 hasRelatedWork W2609332865 @default.
- W1983761330 hasRelatedWork W3043287600 @default.
- W1983761330 hasVolume "779" @default.
- W1983761330 isParatext "false" @default.
- W1983761330 isRetracted "false" @default.
- W1983761330 magId "1983761330" @default.
- W1983761330 workType "article" @default.