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- W1983766024 abstract "A new, solvent-free, vapour-assisted method, developed for the synthesis of carbocyclic cis β-amino acid enantiomers through the Candida antarctica lipase B-catalysed enantioselective (E >200) hydrolysis of β-lactams with 0.5 equiv of H2O at 70 °C, has been demonstrated to be applicable on a preparative scale to produce (±)-2 (the starting racemate for cispentacin), (±)-3 (the starting racemate for 4-tert-butylcispentacin, a new cispentacin analogue) and (±)-7 (the starting racemate for 1,4-ethylene-bridged cispentacin)." @default.
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- W1983766024 date "2008-05-01" @default.
- W1983766024 modified "2023-10-15" @default.
- W1983766024 title "Vapour-assisted enzymatic hydrolysis of β-lactams in a solvent-free system" @default.
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- W1983766024 doi "https://doi.org/10.1016/j.tetasy.2008.04.003" @default.
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