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• W1983770123 abstract "A label-free and enzyme-free sensitive fluorescent detection of human immunodeficiency virus (HIV) deoxyribonucleic acid (DNA) based on isothermal hybridization chain reaction (HCR) was developed. A G-quadruplex sequence which was incorporated into one of the two hairpin probes was inactive in the absence of target DNA. However, at the presence of target DNA numerous G-quadruplexes along DNA nanowires were self-assembled through HCR. Using N-methyl mesoporphyrin IX (NMM) as the fluorophore, a “turn-on” fluorescent response would be achieved and detected as low as 0.5 nmol L−1 of HIV DNA. This proposed method was applied to detect HIV DNA in biologic samples with satisfactory results." @default.
• W1983770123 created "2016-06-24" @default.
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• W1983770123 date "2014-12-01" @default.
• W1983770123 modified "2023-10-16" @default.
• W1983770123 title "Label-free and enzyme-free sensitive fluorescent detection of human immunodeficiency virus deoxyribonucleic acid based on hybridization chain reaction" @default.
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• W1983770123 doi "https://doi.org/10.1016/j.aca.2014.09.032" @default.
• W1983770123 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25441904" @default.
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