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- W1983783908 abstract "Epithelial-to-mesenchymal transition (EMT) is a pathological phenomenon of cancer that confers tumor cells with increased cell motility, invasive and metastatic abilities with the acquisition of 'cancer stem-like cell' (CSC) phenotype. EMT endows tumor cells with intrinsic/acquired resistant phenotype at achievable doses of anticancer drugs and leads to tumor recurrence and progression. Besides the complex network of signaling pathways, microRNAs (miRNAs) are being evolved as a new player in the induction and regulation of EMT.In this review article, the author has searched the PubMed and Google Scholar electronic databases for original research and review articles to gather current information on the association of EMT-induced CSCs with therapeutic resistance, tumor growth and metastasis, which are believed to be regulated by certain miRNAs.This review outlines not only the perspective on selective targeting of EMT-induced CSCs through altered expression of novel miRNAs and/or the use of conventional drugs that affect the levels of critical miRNAs but also the strategies on overcoming the drug resistance by interfering with EMT and modulating its associated pathways in CSCs that can be considered as potential therapeutic approaches toward eradicating the tumor recurrence and metastasis." @default.
- W1983783908 created "2016-06-24" @default.
- W1983783908 creator A5077997584 @default.
- W1983783908 date "2015-01-07" @default.
- W1983783908 modified "2023-10-04" @default.
- W1983783908 title "Targeting microRNAs in epithelial-to-mesenchymal transition-induced cancer stem cells: therapeutic approaches in cancer" @default.
- W1983783908 cites W1488728411 @default.
- W1983783908 cites W1503481430 @default.
- W1983783908 cites W1946577841 @default.
- W1983783908 cites W1964314383 @default.
- W1983783908 cites W1965568527 @default.
- W1983783908 cites W1969985049 @default.
- W1983783908 cites W1972217867 @default.
- W1983783908 cites W1973051645 @default.
- W1983783908 cites W1974012180 @default.
- W1983783908 cites W1977903176 @default.
- W1983783908 cites W1978212773 @default.
- W1983783908 cites W1984781088 @default.
- W1983783908 cites W1989056960 @default.
- W1983783908 cites W1992638032 @default.
- W1983783908 cites W1996118868 @default.
- W1983783908 cites W1996350041 @default.
- W1983783908 cites W1996376317 @default.
- W1983783908 cites W1998857348 @default.
- W1983783908 cites W2000999796 @default.
- W1983783908 cites W2004614813 @default.
- W1983783908 cites W2005894707 @default.
- W1983783908 cites W2006307101 @default.
- W1983783908 cites W2014691022 @default.
- W1983783908 cites W2021958215 @default.
- W1983783908 cites W2028593825 @default.
- W1983783908 cites W2029409898 @default.
- W1983783908 cites W2030575376 @default.
- W1983783908 cites W2030753263 @default.
- W1983783908 cites W2032097464 @default.
- W1983783908 cites W2033320521 @default.
- W1983783908 cites W2036008499 @default.
- W1983783908 cites W2036801235 @default.
- W1983783908 cites W2041891449 @default.
- W1983783908 cites W2050562341 @default.
- W1983783908 cites W2052316732 @default.
- W1983783908 cites W2054030645 @default.
- W1983783908 cites W2058443035 @default.
- W1983783908 cites W2059848983 @default.
- W1983783908 cites W2062398289 @default.
- W1983783908 cites W2073180939 @default.
- W1983783908 cites W2078810029 @default.
- W1983783908 cites W2079863341 @default.
- W1983783908 cites W2082109120 @default.
- W1983783908 cites W2089370460 @default.
- W1983783908 cites W2090570877 @default.
- W1983783908 cites W2096609001 @default.
- W1983783908 cites W2097154005 @default.
- W1983783908 cites W2097739264 @default.
- W1983783908 cites W2102627944 @default.
- W1983783908 cites W2106214862 @default.
- W1983783908 cites W2107607313 @default.
- W1983783908 cites W2108402531 @default.
- W1983783908 cites W2110146698 @default.
- W1983783908 cites W2113584562 @default.
- W1983783908 cites W2119693744 @default.
- W1983783908 cites W2124156632 @default.
- W1983783908 cites W2124488916 @default.
- W1983783908 cites W2125713917 @default.
- W1983783908 cites W2128627710 @default.
- W1983783908 cites W2131596261 @default.
- W1983783908 cites W2135314242 @default.
- W1983783908 cites W2136754349 @default.
- W1983783908 cites W2138343959 @default.
- W1983783908 cites W2140477106 @default.
- W1983783908 cites W2140551998 @default.
- W1983783908 cites W2145063352 @default.
- W1983783908 cites W2146445411 @default.
- W1983783908 cites W2147057201 @default.
- W1983783908 cites W2147807172 @default.
- W1983783908 cites W2150536104 @default.
- W1983783908 cites W2151811239 @default.
- W1983783908 cites W2154589460 @default.
- W1983783908 cites W2166868442 @default.
- W1983783908 cites W2169211736 @default.
- W1983783908 cites W2169444299 @default.
- W1983783908 cites W2170685293 @default.
- W1983783908 doi "https://doi.org/10.1517/14728222.2014.975794" @default.
- W1983783908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25563894" @default.
- W1983783908 hasPublicationYear "2015" @default.
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