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• W1983790321 abstract "BiP is a molecular chaperone induced in the unfolded protein response (UPR). In mammalian cells, BiP is induced by glucose starvation when it is called glucose-regulated protein 78 (GRP78). In Arabidopsis thaliana, however, we demonstrated that BiP transcripts decreased with sugar depletion and increased with sugar addition. Transcripts for β-glucuronidase (GUS) driven by BiP promoter respond to tunicamycin and sugar, being similar with endogenous BiP transcripts in transgenic A. thaliana. When GUS was regulated by P-UPRE, a cis-element responsible for the UPR identified in BiP promoter, GUS transcripts were accumulated by sugar starvation. Subsequently, transgenic A. thaliana harboring luciferase (LUC) gene regulated by P-UPRE was analyzed. Sugar depletion also increased LUC activity. It is concluded that BiP is induced by sugar independent of the cis-element responsible for the UPR." @default.
• W1983790321 created "2016-06-24" @default.
• W1983790321 creator A5061352424 @default.
• W1983790321 creator A5078755481 @default.
• W1983790321 date "2006-08-01" @default.
• W1983790321 modified "2023-09-23" @default.
• W1983790321 title "Induction of BiP by sugar independent of a cis-element for the unfolded protein response in Arabidopsis thaliana" @default.
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• W1983790321 doi "https://doi.org/10.1016/j.bbrc.2006.05.189" @default.
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