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- W198380215 abstract "It is the process of metastasis in cancer which impairs the ability of surgery to cure all but its earliest stages. In histologic observations of carcinomas, it is generally noted that as epithelial growth becomes dysregulated, the stromal-epithelial tissue compartmentalization also can become disturbed. The dissolution of the epithelial basement membrane signals local invasion of the disease; blood vessel infiltration (angiogenesis) is thought to allow the tumor cells to spread via lymphatic and hematogenous means to nearby and to distant organs. Metastasis is thought to depend upon alterations in cell adhesion, motility, proteolysis, and the ability to survive in another organ’s environments." @default.
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- W198380215 date "1995-01-01" @default.
- W198380215 modified "2023-09-27" @default.
- W198380215 title "Stromal—epithelial interaction in type IV collagenase expression and activation: The role in cancer metastasis" @default.
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- W198380215 doi "https://doi.org/10.1007/978-3-0348-9070-0_11" @default.
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