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• W1983808262 abstract "We thank Drs. Parkash and Tang for their interest in our recent work. The authors outlined that additional substrate ablation beyond the pulmonary veins is required in patients with persistent atrial fibrillation (AF); however, it does result in similar outcomes irrespective to the approach used to target the substrate. This is true when recurrences are not further classified according to arrhythmia mechanism. When arrhythmia recurrences are distinguished between AF and atrial tachycardia (AT), the impact of ablation complexity becomes evident: an increasing extensiveness of substrate ablation is associated with a decrease of AF and increase of AT recurrences. 1 Elayi C.S. Verma A. Di Biase L. et al. Ablation of longstanding permanent atrial fibrillation: results from a randomized study comparing three different strategies. Heart Rhythm. 2008; 5: 1658-1664 Abstract Full Text Full Text PDF PubMed Scopus (274) Google Scholar , 2 Nademanee K. McKenzie J. Kosar E. et al. A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate. J Am Coll Cardiol. 2004; 43: 2044-2053 Abstract Full Text Full Text PDF PubMed Scopus (1714) Google Scholar , 3 Rostock T. Salukhe T.V. Steven D. et al. Long-term single- and multiple-procedure outcome and predictors of success after catheter ablation for persistent atrial fibrillation. Heart Rhythm. 2011; 8: 1391-1397 Abstract Full Text Full Text PDF PubMed Scopus (174) Google Scholar Furthermore, the distinction of the mode of recurrent arrhythmia is of particular importance because recurrence of AT is considered a step forward on the way to sinus rhythm. 3 Rostock T. Salukhe T.V. Steven D. et al. Long-term single- and multiple-procedure outcome and predictors of success after catheter ablation for persistent atrial fibrillation. Heart Rhythm. 2011; 8: 1391-1397 Abstract Full Text Full Text PDF PubMed Scopus (174) Google Scholar , 4 Ammar S. Hessling G. Reents T. et al. Arrhythmia type after persistent atrial fibrillation ablation predicts success of the repeat procedure. Circ Arrhythm Electrophysiol. 2011; 4: 609-614 Crossref PubMed Scopus (49) Google Scholar To the Editor–Ablation of persistent atrial fibrillationHeart RhythmVol. 9Issue 2PreviewRostock et al1 confirm the difficulty faced in the ablation of persistent atrial fibrillation (AF) in their study examining the long-term success of catheter ablation in this group of patients, with a single procedure efficacy at 27%. They comment on atrial substrate modification with various approaches to catheter ablation. We believe that the substrate—both electrophysiological and structural—is crucial to address in patients with persistent AF. We found in a meta-analysis of randomized studies of catheter ablation in AF that irrespective of the approach used in persistent AF in addition to pulmonary vein isolation, the results are similar. Full-Text PDF" @default.
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• W1983808262 date "2012-02-01" @default.
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• W1983808262 title "Reply to the Editor—Persistent Atrial Fibrillation" @default.
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• W1983808262 doi "https://doi.org/10.1016/j.hrthm.2011.11.016" @default.
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