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- W1983818274 abstract "This chapter discusses the action of thyrotropin on thyroid metabolism. Growth and function of the thyroid are mainly controlled by the level of thyrotropin (TSH) concentration in the plasma. The principal element of this control, the action of TSH on its target, the thyroid follicular cell, has been investigated intensively during recent years. TSH activates rapidly the steps of thyroidal iodine metabolism—that is, the formation of thyroid hormones from iodide and tyrosines and the secretion of these hormones, and induces, after a delay, the growth of thyroid tissue. Among the various systems available for the study of the interaction of a tropic hormone with its target cell, the thyroid and TSH present several advantages and disadvantages. The specialized metabolism of the follicular cell, the metabolism of iodine, is easily studied with the various radioisotopes of iodine. Thyroid tissue is very resistant to adverse conditions, which explains the great stability and the great variety of in vitro thyroid systems." @default.
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- W1983818274 date "1967-12-01" @default.
- W1983818274 modified "2023-09-25" @default.
- W1983818274 title "Thyrotropin stimulation of pyrimidine nucleotide synthesis in bovine thyroid" @default.
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- W1983818274 doi "https://doi.org/10.1016/0006-291x(67)90297-5" @default.
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