Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983822563> ?p ?o ?g. }
- W1983822563 endingPage "2280" @default.
- W1983822563 startingPage "2277" @default.
- W1983822563 abstract "SARS-CoV2 might conduce to rapid respiratory complications challenging healthcare systems worldwide. Immunological mechanisms associated to SARS-CoV2 infection are complex and not yet clearly elucidated. Arguments are in favour of a well host-adapted virus. Here I draw a systemic immunological representation linking actual SARS-CoV2 infection literature that hopefully might guide healthcare decisions to treat COVID-19. I suggest HLA-G and HLA-E, non classical HLA class I molecules, in the core of COVID-19 complications. These molecules are powerful in immune tolerance and might inhibit/suppress immune cells functions during SARS-CoV2 infection promoting virus subversion. Dosing soluble forms of these molecules in COVID-19 patients’ plasma might help the identification of critical cases. I recommend also developing new SARS-CoV2 therapies based on the use of HLA-G and HLA-E or their specific receptors antibodies in combination with FDA approved therapeutics to combat efficiently COVID-19." @default.
- W1983822563 created "2016-06-24" @default.
- W1983822563 creator A5006123503 @default.
- W1983822563 creator A5006529031 @default.
- W1983822563 creator A5030344846 @default.
- W1983822563 creator A5039369336 @default.
- W1983822563 creator A5041378929 @default.
- W1983822563 creator A5043224929 @default.
- W1983822563 creator A5048045002 @default.
- W1983822563 creator A5075573725 @default.
- W1983822563 creator A5084630790 @default.
- W1983822563 date "2001-05-01" @default.
- W1983822563 modified "2023-09-27" @default.
- W1983822563 title "Glucocorticoid hormones upregulate levels of HLA-G transcripts in trophoblasts" @default.
- W1983822563 cites W1639895894 @default.
- W1983822563 cites W1745264954 @default.
- W1983822563 cites W1787685519 @default.
- W1983822563 cites W1964935231 @default.
- W1983822563 cites W1976677947 @default.
- W1983822563 cites W1986672594 @default.
- W1983822563 cites W2020328448 @default.
- W1983822563 cites W2022894063 @default.
- W1983822563 cites W2041001602 @default.
- W1983822563 cites W2049912478 @default.
- W1983822563 cites W2050275562 @default.
- W1983822563 cites W2051716667 @default.
- W1983822563 cites W2068943233 @default.
- W1983822563 cites W2080999185 @default.
- W1983822563 cites W2090979652 @default.
- W1983822563 cites W2100279258 @default.
- W1983822563 cites W2102151740 @default.
- W1983822563 cites W2108463809 @default.
- W1983822563 cites W2122120727 @default.
- W1983822563 cites W2137563190 @default.
- W1983822563 cites W2158110584 @default.
- W1983822563 cites W2167206160 @default.
- W1983822563 cites W4232974402 @default.
- W1983822563 cites W4252002273 @default.
- W1983822563 cites W4253919924 @default.
- W1983822563 cites W4256630902 @default.
- W1983822563 doi "https://doi.org/10.1016/s0041-1345(01)01990-x" @default.
- W1983822563 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11377528" @default.
- W1983822563 hasPublicationYear "2001" @default.
- W1983822563 type Work @default.
- W1983822563 sameAs 1983822563 @default.
- W1983822563 citedByCount "72" @default.
- W1983822563 countsByYear W19838225632012 @default.
- W1983822563 countsByYear W19838225632014 @default.
- W1983822563 countsByYear W19838225632015 @default.
- W1983822563 countsByYear W19838225632016 @default.
- W1983822563 countsByYear W19838225632017 @default.
- W1983822563 countsByYear W19838225632018 @default.
- W1983822563 countsByYear W19838225632019 @default.
- W1983822563 countsByYear W19838225632020 @default.
- W1983822563 countsByYear W19838225632021 @default.
- W1983822563 countsByYear W19838225632022 @default.
- W1983822563 crossrefType "journal-article" @default.
- W1983822563 hasAuthorship W1983822563A5006123503 @default.
- W1983822563 hasAuthorship W1983822563A5006529031 @default.
- W1983822563 hasAuthorship W1983822563A5030344846 @default.
- W1983822563 hasAuthorship W1983822563A5039369336 @default.
- W1983822563 hasAuthorship W1983822563A5041378929 @default.
- W1983822563 hasAuthorship W1983822563A5043224929 @default.
- W1983822563 hasAuthorship W1983822563A5048045002 @default.
- W1983822563 hasAuthorship W1983822563A5075573725 @default.
- W1983822563 hasAuthorship W1983822563A5084630790 @default.
- W1983822563 hasConcept C126322002 @default.
- W1983822563 hasConcept C147483822 @default.
- W1983822563 hasConcept C188280979 @default.
- W1983822563 hasConcept C203014093 @default.
- W1983822563 hasConcept C2522874641 @default.
- W1983822563 hasConcept C2779134260 @default.
- W1983822563 hasConcept C3008058167 @default.
- W1983822563 hasConcept C524204448 @default.
- W1983822563 hasConcept C71315377 @default.
- W1983822563 hasConcept C71924100 @default.
- W1983822563 hasConcept C86803240 @default.
- W1983822563 hasConcept C8891405 @default.
- W1983822563 hasConcept C89623803 @default.
- W1983822563 hasConceptScore W1983822563C126322002 @default.
- W1983822563 hasConceptScore W1983822563C147483822 @default.
- W1983822563 hasConceptScore W1983822563C188280979 @default.
- W1983822563 hasConceptScore W1983822563C203014093 @default.
- W1983822563 hasConceptScore W1983822563C2522874641 @default.
- W1983822563 hasConceptScore W1983822563C2779134260 @default.
- W1983822563 hasConceptScore W1983822563C3008058167 @default.
- W1983822563 hasConceptScore W1983822563C524204448 @default.
- W1983822563 hasConceptScore W1983822563C71315377 @default.
- W1983822563 hasConceptScore W1983822563C71924100 @default.
- W1983822563 hasConceptScore W1983822563C86803240 @default.
- W1983822563 hasConceptScore W1983822563C8891405 @default.
- W1983822563 hasConceptScore W1983822563C89623803 @default.
- W1983822563 hasIssue "3" @default.
- W1983822563 hasLocation W19838225631 @default.
- W1983822563 hasLocation W19838225632 @default.
- W1983822563 hasLocation W19838225633 @default.
- W1983822563 hasLocation W19838225634 @default.
- W1983822563 hasOpenAccess W1983822563 @default.