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- W1983826679 abstract "Abstract Renal diseases are prevalent and important. However, despite significant strides in medicine, clinical nephrology still relies on nonspecific and inadequate markers such as serum creatinine and total urine protein for monitoring and diagnosis of renal disease. In case of glomerular renal diseases, biopsy is often necessary to establish the diagnosis. With new developments in proteomics technology, numerous studies have emerged, searching for better markers of kidney disease diagnosis and/or prognosis. Blood, urine, and renal biopsy tissue have been explored as potential sources of biomarkers. Some interesting individual or multiparametric biomarkers have been found; however, none have yet been validated or entered clinical practice. This review focuses on some studies of biomarkers of glomerular renal diseases, as well as addresses the question of which sample type(s) might be most promising in preliminary discovery phases of candidate proteins." @default.
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- W1983826679 date "2010-06-11" @default.
- W1983826679 modified "2023-09-23" @default.
- W1983826679 title "The Quest for Renal Disease Proteomic Signatures: Where Should We Look?" @default.
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- W1983826679 doi "https://doi.org/10.1007/s12014-010-9047-y" @default.
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