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- W1983842212 abstract "Abstract The Egyptian toads, Bufo regularis , were divided into 5 groups, 100 each. Injections of 7,12-dimethylbenz(a)anthracene (DMBA) into the dorsal lymph sacs of toads induced liver tumors in 12% of the animals tested (12 toads out of 100 toads). The dose was 4mg/40g body weight administered once a week for 3 months. Toads treated with DMBA at the same dose level were subjected to commercial corn oil orally at dose levels 2cc/week, 2cc twice/week, 2cc 3 times/week. They showed higher incidence of liver tumors of 24%. 48% and 66% for the variable dose levels respectively. The minimum dose which increased tumor incidence was 2cc/week. It is concluded that the Egyptian toad can be used as a sensitive model for detecting the promoting effect of corn oil on liver tumors induced by DMBA." @default.
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- W1983842212 date "1986-03-01" @default.
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- W1983842212 title "The Egyptian toad as a sensitive model to show the effect of corn oil on liver tumor induced by DMBA" @default.
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- W1983842212 doi "https://doi.org/10.1016/s0271-5317(86)80137-3" @default.
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