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• W1983917428 abstract "We found that transcription of NOR‐1 (neuron‐derived orphan receptor‐1) is induced by the Ca 2+ /calmodulin‐dependent protein kinase IV (CaM‐KIV) cascade by differential hybridization screening of a cDNA array using probes prepared from SH‐SY5Y cells infected with recombinant adenoviruses expressing Ca 2+ /CaM‐independent mutants of CaM‐KIV and CaM‐K kinase (CaM‐KK). Induction of NOR‐1 mRNA expression by the CaM‐KIV cascade was confirmed by RT‐PCR. Promoter analyses indicate that CaM‐KIV cascade response element is located between −162 bp and −42 bp in the 1.7 kb NOR‐1 promoter containing triple cAMP response elements. Disruption of each element significantly reduced the promoter activity, indicating the direct transcriptional regulation of NOR‐1 by CaM‐KIV cascade." @default.
• W1983917428 created "2016-06-24" @default.
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• W1983917428 date "2002-06-05" @default.
• W1983917428 modified "2023-09-25" @default.
• W1983917428 title "Transcriptional regulation of nuclear orphan receptor,<i>NOR-1</i>, by Ca²⁺/calmodulin-dependent protein kinase cascade" @default.
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• W1983917428 doi "https://doi.org/10.1016/s0014-5793(02)02890-9" @default.
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