FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983941993> ?p ?o ?g. }

• W1983941993 endingPage "288" @default.
• W1983941993 startingPage "271" @default.
• W1983941993 abstract "Cell-penetrating peptides (CPPs) are able to translocate and carry cargo molecules across cell membranes. Using fluorescence techniques (polarization and quenching) and CD spectroscopy we studied the interaction, conformation and topology of two such peptides, transportan and 'penetratin' (pAntp), and two variants of differing translocating abilities, with small phospholipid vesicles of varying charge density. The induced structure of transportan is always helical independent of vesicle surface charge. pAntp and its two variants interact significantly only with negatively charged vesicles. The induced secondary structure depends on membrane charge and lipid/peptide ratio. The degree of membrane perturbation, evidenced by fluorescence polarization, of pAntp and its variants is related to their secondary structure. In the helical state, the peptides have little effect on the membrane. Under conditions where pAntp and its variants are converted into beta-structures, they cause membrane perturbation. Oriented CD suggests that the two CPPs (pAntp and transportan) in their helical state lie along the vesicle surface, while the two pAntp variants appear to penetrate deeper into the membrane." @default.
• W1983941993 created "2016-06-24" @default.
• W1983941993 creator A5017983040 @default.
• W1983941993 creator A5034635485 @default.
• W1983941993 creator A5090994819 @default.
• W1983941993 date "2003-03-01" @default.
• W1983941993 modified "2023-10-16" @default.
• W1983941993 title "Comparison of the interaction, positioning, structure induction and membrane perturbation of cell-penetrating peptides and non-translocating variants with phospholipid vesicles" @default.
• W1983941993 cites W1558087535 @default.
• W1983941993 cites W1574601702 @default.
• W1983941993 cites W1584683177 @default.
• W1983941993 cites W1965434479 @default.
• W1983941993 cites W1972711580 @default.
• W1983941993 cites W1973109843 @default.
• W1983941993 cites W1974633538 @default.
• W1983941993 cites W1983351621 @default.
• W1983941993 cites W1989410545 @default.
• W1983941993 cites W1990550092 @default.
• W1983941993 cites W1992178795 @default.
• W1983941993 cites W1997332996 @default.
• W1983941993 cites W1999745309 @default.
• W1983941993 cites W2013994501 @default.
• W1983941993 cites W2017814330 @default.
• W1983941993 cites W2026597183 @default.
• W1983941993 cites W2031620423 @default.
• W1983941993 cites W2034531716 @default.
• W1983941993 cites W2038720675 @default.
• W1983941993 cites W2042153675 @default.
• W1983941993 cites W2047887742 @default.
• W1983941993 cites W2050815417 @default.
• W1983941993 cites W2052886000 @default.
• W1983941993 cites W2057609017 @default.
• W1983941993 cites W2057870351 @default.
• W1983941993 cites W2060619977 @default.
• W1983941993 cites W2061012754 @default.
• W1983941993 cites W2062005486 @default.
• W1983941993 cites W2080633604 @default.
• W1983941993 cites W2082620986 @default.
• W1983941993 cites W2087917270 @default.
• W1983941993 cites W2099559490 @default.
• W1983941993 cites W2100594357 @default.
• W1983941993 cites W2128125971 @default.
• W1983941993 cites W2155482026 @default.
• W1983941993 cites W2158043431 @default.
• W1983941993 cites W2171846923 @default.
• W1983941993 cites W4242389407 @default.
• W1983941993 cites W4245676270 @default.
• W1983941993 doi "https://doi.org/10.1016/s0301-4622(02)00321-6" @default.
• W1983941993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12727289" @default.
• W1983941993 hasPublicationYear "2003" @default.
• W1983941993 type Work @default.
• W1983941993 sameAs 1983941993 @default.
• W1983941993 citedByCount "100" @default.
• W1983941993 countsByYear W19839419932012 @default.
• W1983941993 countsByYear W19839419932013 @default.
• W1983941993 countsByYear W19839419932014 @default.
• W1983941993 countsByYear W19839419932015 @default.
• W1983941993 countsByYear W19839419932016 @default.
• W1983941993 countsByYear W19839419932017 @default.
• W1983941993 countsByYear W19839419932018 @default.
• W1983941993 countsByYear W19839419932019 @default.
• W1983941993 countsByYear W19839419932020 @default.
• W1983941993 countsByYear W19839419932021 @default.
• W1983941993 countsByYear W19839419932023 @default.
• W1983941993 crossrefType "journal-article" @default.
• W1983941993 hasAuthorship W1983941993A5017983040 @default.
• W1983941993 hasAuthorship W1983941993A5034635485 @default.
• W1983941993 hasAuthorship W1983941993A5090994819 @default.
• W1983941993 hasConcept C111357860 @default.
• W1983941993 hasConcept C12554922 @default.
• W1983941993 hasConcept C130316041 @default.
• W1983941993 hasConcept C185592680 @default.
• W1983941993 hasConcept C2776929087 @default.
• W1983941993 hasConcept C2778106830 @default.
• W1983941993 hasConcept C2778918659 @default.
• W1983941993 hasConcept C2779281246 @default.
• W1983941993 hasConcept C39944091 @default.
• W1983941993 hasConcept C41625074 @default.
• W1983941993 hasConcept C55493867 @default.
• W1983941993 hasConcept C62614982 @default.
• W1983941993 hasConcept C86803240 @default.
• W1983941993 hasConcept C96347405 @default.
• W1983941993 hasConceptScore W1983941993C111357860 @default.
• W1983941993 hasConceptScore W1983941993C12554922 @default.
• W1983941993 hasConceptScore W1983941993C130316041 @default.
• W1983941993 hasConceptScore W1983941993C185592680 @default.
• W1983941993 hasConceptScore W1983941993C2776929087 @default.
• W1983941993 hasConceptScore W1983941993C2778106830 @default.
• W1983941993 hasConceptScore W1983941993C2778918659 @default.
• W1983941993 hasConceptScore W1983941993C2779281246 @default.
• W1983941993 hasConceptScore W1983941993C39944091 @default.
• W1983941993 hasConceptScore W1983941993C41625074 @default.
• W1983941993 hasConceptScore W1983941993C55493867 @default.
• W1983941993 hasConceptScore W1983941993C62614982 @default.
• W1983941993 hasConceptScore W1983941993C86803240 @default.
• W1983941993 hasConceptScore W1983941993C96347405 @default.
• W1983941993 hasIssue "3" @default.
• W1983941993 hasLocation W19839419931 @default.

• next