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- W1983983721 abstract "The consumption of alcohol in man appears to be inversely related to the incidence of.coronary heart disease (CHD) (1). It seems that this beneficial effect of alcohol is not related to a lowering of blood lipids since alcohol is known to be hypertriglyceridemic (2). Studies in French farmers (3), confirmed in more extensive investigations in French and British farmers (4) have shown that platelet clotting activity and platelet aggregation induced by thrombin, but mostly by ADP, epinephrine and collagen, were inversely related to the alcohol intake. Platelets appear to be closely associated with CW being involved not only in thrombosis but also in early atherosclerotic lesions (5). In our studies in farmers, we have shown that platelet functions were the only blood parameter significantly correlated with the intake of sa' turated fat (4), the environmental factor the most closely assotiiated with CHD (6). In the present study in rats fed saturated or polyunsaturated fats, we have observed that alcohol, both in vivo and in vitro, inhibits certain platelet functions, chiefly in animals fed a saturated diet." @default.
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- W1983983721 date "1981-04-01" @default.
- W1983983721 modified "2023-09-26" @default.
- W1983983721 title "Inhibitory effect of alcohol on platelet functions of rats fed saturated fats" @default.
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- W1983983721 doi "https://doi.org/10.1016/0049-3848(81)90324-8" @default.
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