FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983989657> ?p ?o ?g. }

• W1983989657 endingPage "563" @default.
• W1983989657 startingPage "555" @default.
• W1983989657 abstract "Prognosis of patients with hepatocellular carcinoma (HCC) remains poor because HCC is frequently diagnosed late. Therefore, regular surveillance has been recommended to detect HCC at the early stage when curative treatments can be applied. HCC biomarkers, including Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3), are widely used for surveillance in Japan. A newly developed immunoassay system measures AFP-L3 % with high sensitivity. This retrospective study aimed to evaluate clinical utility of high-sensitivity AFP-L3 (hs-AFP-L3) as a predictor of early stage HCC in surveillance at a single site.Of consecutive 2830 patients in the surveillance between 2000 and 2009, 104 HCC-developed and 104 non-HCC patients were selected by eligibility criteria and propensity score matching. Samples were obtained from the HCC patients who had blood drawn annually for 3 years prior to HCC diagnosis.In the present study, hs-AFP-L3 was elevated 1 year prior to diagnosis in 34.3 % of patients. The survival rate of patients with the hs-AFP-L3 ≥ 7 % at 1 year prior to diagnosis was significantly lower than that of patients with hs-AFP-L3 < 7 %.Elevation of hs-AFP-L3 was early predictive of development of HCC even at low AFP levels and in absence of ultrasound findings of suspicious HCC. The hs-AFP-L3 should be added to surveillance programs with US because elevated hs-AFP-L3 may be a trigger to perform enhanced imaging modalities for confirmation of HCC." @default.
• W1983989657 created "2016-06-24" @default.
• W1983989657 creator A5008619085 @default.
• W1983989657 creator A5017515823 @default.
• W1983989657 creator A5026964230 @default.
• W1983989657 creator A5027001120 @default.
• W1983989657 creator A5032472868 @default.
• W1983989657 creator A5036994958 @default.
• W1983989657 creator A5043581157 @default.
• W1983989657 creator A5043762552 @default.
• W1983989657 creator A5068214058 @default.
• W1983989657 creator A5081418955 @default.
• W1983989657 date "2013-09-23" @default.
• W1983989657 modified "2023-10-03" @default.
• W1983989657 title "High-sensitivity Lens culinaris agglutinin-reactive alpha-fetoprotein assay predicts early detection of hepatocellular carcinoma" @default.
• W1983989657 cites W1539891810 @default.
• W1983989657 cites W1873285239 @default.
• W1983989657 cites W1965980171 @default.
• W1983989657 cites W1981989535 @default.
• W1983989657 cites W1989182649 @default.
• W1983989657 cites W1994850200 @default.
• W1983989657 cites W1996523527 @default.
• W1983989657 cites W1999772124 @default.
• W1983989657 cites W2000001318 @default.
• W1983989657 cites W2007861184 @default.
• W1983989657 cites W2013256718 @default.
• W1983989657 cites W2020215421 @default.
• W1983989657 cites W2020494673 @default.
• W1983989657 cites W2026347117 @default.
• W1983989657 cites W2027179322 @default.
• W1983989657 cites W2031007088 @default.
• W1983989657 cites W2047554241 @default.
• W1983989657 cites W2051552936 @default.
• W1983989657 cites W2058719417 @default.
• W1983989657 cites W2077267329 @default.
• W1983989657 cites W2084868600 @default.
• W1983989657 cites W2127073448 @default.
• W1983989657 cites W2135201074 @default.
• W1983989657 cites W2145788008 @default.
• W1983989657 cites W2158215714 @default.
• W1983989657 cites W2163403599 @default.
• W1983989657 cites W2170740692 @default.
• W1983989657 cites W4245881395 @default.
• W1983989657 cites W4299689471 @default.
• W1983989657 doi "https://doi.org/10.1007/s00535-013-0883-1" @default.
• W1983989657 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3953543" @default.
• W1983989657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24057163" @default.
• W1983989657 hasPublicationYear "2013" @default.
• W1983989657 type Work @default.
• W1983989657 sameAs 1983989657 @default.
• W1983989657 citedByCount "54" @default.
• W1983989657 countsByYear W19839896572013 @default.
• W1983989657 countsByYear W19839896572014 @default.
• W1983989657 countsByYear W19839896572015 @default.
• W1983989657 countsByYear W19839896572016 @default.
• W1983989657 countsByYear W19839896572017 @default.
• W1983989657 countsByYear W19839896572018 @default.
• W1983989657 countsByYear W19839896572019 @default.
• W1983989657 countsByYear W19839896572020 @default.
• W1983989657 countsByYear W19839896572021 @default.
• W1983989657 countsByYear W19839896572022 @default.
• W1983989657 countsByYear W19839896572023 @default.
• W1983989657 crossrefType "journal-article" @default.
• W1983989657 hasAuthorship W1983989657A5008619085 @default.
• W1983989657 hasAuthorship W1983989657A5017515823 @default.
• W1983989657 hasAuthorship W1983989657A5026964230 @default.
• W1983989657 hasAuthorship W1983989657A5027001120 @default.
• W1983989657 hasAuthorship W1983989657A5032472868 @default.
• W1983989657 hasAuthorship W1983989657A5036994958 @default.
• W1983989657 hasAuthorship W1983989657A5043581157 @default.
• W1983989657 hasAuthorship W1983989657A5043762552 @default.
• W1983989657 hasAuthorship W1983989657A5068214058 @default.
• W1983989657 hasAuthorship W1983989657A5081418955 @default.
• W1983989657 hasBestOaLocation W19839896571 @default.
• W1983989657 hasConcept C126322002 @default.
• W1983989657 hasConcept C146357865 @default.
• W1983989657 hasConcept C151730666 @default.
• W1983989657 hasConcept C2778019345 @default.
• W1983989657 hasConcept C2780140570 @default.
• W1983989657 hasConcept C2780624289 @default.
• W1983989657 hasConcept C41260117 @default.
• W1983989657 hasConcept C71924100 @default.
• W1983989657 hasConcept C86803240 @default.
• W1983989657 hasConcept C90924648 @default.
• W1983989657 hasConceptScore W1983989657C126322002 @default.
• W1983989657 hasConceptScore W1983989657C146357865 @default.
• W1983989657 hasConceptScore W1983989657C151730666 @default.
• W1983989657 hasConceptScore W1983989657C2778019345 @default.
• W1983989657 hasConceptScore W1983989657C2780140570 @default.
• W1983989657 hasConceptScore W1983989657C2780624289 @default.
• W1983989657 hasConceptScore W1983989657C41260117 @default.
• W1983989657 hasConceptScore W1983989657C71924100 @default.
• W1983989657 hasConceptScore W1983989657C86803240 @default.
• W1983989657 hasConceptScore W1983989657C90924648 @default.
• W1983989657 hasIssue "3" @default.
• W1983989657 hasLocation W19839896571 @default.
• W1983989657 hasLocation W19839896572 @default.
• W1983989657 hasLocation W19839896573 @default.

• next