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- W1984004768 abstract "Agonist-stimulated changes in D-Ins(1,4,5)P3 has been examined in tracheal smooth muscle using a specific radioreceptor assay utilizing the binding of [3H] or [32P]Ins(1,4,5)P3 to a bovine adrenal cortex preparation. Carbachol produced a maximal increase in Ins(1,4,5)P3 concentration after 5 s (basal: 12.9 +/- 0.8; stimulated: 27 +/- 1.5 pmol/mg protein) with an EC50 of 6.7 +/- 0.8 microM. With longer stimulation periods Ins(1,4,5)P3 rapidly returned to basal values by 30 s. This is the first report of mass measurements of Ins(1,4,5)P3 in smooth muscle." @default.
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- W1984004768 date "1989-05-01" @default.
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- W1984004768 title "Mass changes of inositol(1,4,5) trisphosphate in trachealis muscle following agonist stimulation" @default.
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- W1984004768 doi "https://doi.org/10.1016/0014-2999(89)90269-0" @default.
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