Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984006908> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1984006908 endingPage "64" @default.
- W1984006908 startingPage "58" @default.
- W1984006908 abstract "Background : In addition to histamine, mast cells contain other potent mediators which can contribute to the allergic wheal reaction in the skin. Methods : To study the association of tryptase‐, chymase‐, and interleukin‐4 (IL‐4)‐positive mast cells with the size of the prick‐test wheal reaction, 50 sensitive atopic subjects were prick‐tested with the cow‐dander allergen on the forearm skin, and the wheal area was measured. A corresponding site of intact healthy‐looking skin was biopsied and examined enzyme‐histochemically for tryptase and chymase. A double‐staining method was used to demonstrate the immunoreactivity of IL‐4 and chymase inhibitors (α 1 ‐proteinase inhibitor and α 1 ‐antichymotrypsin) in mast cells. The levels of total and cow‐specific immunoglobulin E (IgE) were measured in serum. Results : The number of tryptase‐ and chymase‐positive mast cells or those containing chymase inhibitors revealed no correlation with the wheal reaction. In contrast, both the percentage and the number of IL‐4‐positive mast cells showed significant positive correlation with the wheal size per se ( P <0.0001), as well as with the ratio of the wheal size by cow allergen to that by histamine control ( P <0.003). In addition, tryptase‐, chymase‐, and IL‐4‐positive mast cells correlated with total IgE, but not with specific IgE, levels, and they showed no relation to the clinical manifestation of atopic disease, asthma or atopic dermatitis. Conclusions : The novel finding was that IL‐4‐positive, but not tryptase‐ and chymase‐positive, mast cells are intimately associated with the extent of the prick‐test wheal." @default.
- W1984006908 created "2016-06-24" @default.
- W1984006908 creator A5003020301 @default.
- W1984006908 creator A5019198615 @default.
- W1984006908 creator A5044877234 @default.
- W1984006908 creator A5057072408 @default.
- W1984006908 creator A5077403023 @default.
- W1984006908 date "2001-01-01" @default.
- W1984006908 modified "2023-10-18" @default.
- W1984006908 title "Interleukin-4-positive mast cells are highly associated with the extent of immediate allergic wheal reaction in the skin" @default.
- W1984006908 cites W1504566925 @default.
- W1984006908 cites W1529918408 @default.
- W1984006908 cites W1549183351 @default.
- W1984006908 cites W1836425824 @default.
- W1984006908 cites W1963169432 @default.
- W1984006908 cites W1966584334 @default.
- W1984006908 cites W1982320148 @default.
- W1984006908 cites W1998539607 @default.
- W1984006908 cites W1999760874 @default.
- W1984006908 cites W2001687270 @default.
- W1984006908 cites W2024833436 @default.
- W1984006908 cites W2026168420 @default.
- W1984006908 cites W2043524766 @default.
- W1984006908 cites W2057203934 @default.
- W1984006908 cites W2069174048 @default.
- W1984006908 cites W2069596641 @default.
- W1984006908 cites W2069808501 @default.
- W1984006908 cites W2071094160 @default.
- W1984006908 cites W2080962013 @default.
- W1984006908 cites W2082218171 @default.
- W1984006908 cites W2088174667 @default.
- W1984006908 cites W2091416030 @default.
- W1984006908 cites W2119538799 @default.
- W1984006908 cites W2127882630 @default.
- W1984006908 cites W2151900684 @default.
- W1984006908 cites W2169100849 @default.
- W1984006908 cites W2171961734 @default.
- W1984006908 cites W4313335099 @default.
- W1984006908 doi "https://doi.org/10.1034/j.1398-9995.2001.00833.x" @default.
- W1984006908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11167353" @default.
- W1984006908 hasPublicationYear "2001" @default.
- W1984006908 type Work @default.
- W1984006908 sameAs 1984006908 @default.
- W1984006908 citedByCount "15" @default.
- W1984006908 countsByYear W19840069082013 @default.
- W1984006908 countsByYear W19840069082016 @default.
- W1984006908 countsByYear W19840069082018 @default.
- W1984006908 crossrefType "journal-article" @default.
- W1984006908 hasAuthorship W1984006908A5003020301 @default.
- W1984006908 hasAuthorship W1984006908A5019198615 @default.
- W1984006908 hasAuthorship W1984006908A5044877234 @default.
- W1984006908 hasAuthorship W1984006908A5057072408 @default.
- W1984006908 hasAuthorship W1984006908A5077403023 @default.
- W1984006908 hasConcept C1122143 @default.
- W1984006908 hasConcept C126322002 @default.
- W1984006908 hasConcept C141105273 @default.
- W1984006908 hasConcept C159654299 @default.
- W1984006908 hasConcept C203014093 @default.
- W1984006908 hasConcept C207480886 @default.
- W1984006908 hasConcept C2778329239 @default.
- W1984006908 hasConcept C2779726688 @default.
- W1984006908 hasConcept C2780510475 @default.
- W1984006908 hasConcept C2780614898 @default.
- W1984006908 hasConcept C2781406822 @default.
- W1984006908 hasConcept C71924100 @default.
- W1984006908 hasConceptScore W1984006908C1122143 @default.
- W1984006908 hasConceptScore W1984006908C126322002 @default.
- W1984006908 hasConceptScore W1984006908C141105273 @default.
- W1984006908 hasConceptScore W1984006908C159654299 @default.
- W1984006908 hasConceptScore W1984006908C203014093 @default.
- W1984006908 hasConceptScore W1984006908C207480886 @default.
- W1984006908 hasConceptScore W1984006908C2778329239 @default.
- W1984006908 hasConceptScore W1984006908C2779726688 @default.
- W1984006908 hasConceptScore W1984006908C2780510475 @default.
- W1984006908 hasConceptScore W1984006908C2780614898 @default.
- W1984006908 hasConceptScore W1984006908C2781406822 @default.
- W1984006908 hasConceptScore W1984006908C71924100 @default.
- W1984006908 hasIssue "1" @default.
- W1984006908 hasLocation W19840069081 @default.
- W1984006908 hasLocation W19840069082 @default.
- W1984006908 hasOpenAccess W1984006908 @default.
- W1984006908 hasPrimaryLocation W19840069081 @default.
- W1984006908 hasRelatedWork W1951686243 @default.
- W1984006908 hasRelatedWork W1992235949 @default.
- W1984006908 hasRelatedWork W1999064172 @default.
- W1984006908 hasRelatedWork W2019100913 @default.
- W1984006908 hasRelatedWork W2061316941 @default.
- W1984006908 hasRelatedWork W2144251956 @default.
- W1984006908 hasRelatedWork W2147110507 @default.
- W1984006908 hasRelatedWork W2173633259 @default.
- W1984006908 hasRelatedWork W2416302103 @default.
- W1984006908 hasRelatedWork W4236001543 @default.
- W1984006908 hasVolume "56" @default.
- W1984006908 isParatext "false" @default.
- W1984006908 isRetracted "false" @default.
- W1984006908 magId "1984006908" @default.
- W1984006908 workType "article" @default.