Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984025579> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1984025579 endingPage "131" @default.
- W1984025579 startingPage "124" @default.
- W1984025579 abstract "Plasma (P), synovial fluid (SF) and lymph (L) concentrations of gentamicin were studied in two trials. A lymph vessel in the hindlimb was cannulated. The day after surgery (trial A), P and L samples were collected for 12 h after intravenous injection of gentamicin sulphate at 2.2 mg/kg dose rate. Approximately 48 h after surgery (trial B), the fetlock joint of the cannulated hindlimb was catheterized and P, SF and L samples collected for 12 h after a similar intravenous injection. The kinetic parameters were similar to those in other reports and did not differ between trials (P < 0.05). The P, L and SF disposition profiles were similar. The 95% confidence interval for P & L concentrations overlapped 2-3 h after injection. Thereafter, parallelism between L and P concentrations was observed, but L concentrations were on average 60% higher than P concentrations, and elimination from L was slower than from P. The mean L/SF and P/SF ratios were 1.54 +/- 0.2 and 1.25 +/- 0.2, 2-4 h after injection. Gentamicin elimination from SF appeared to be slower than from L and P. Lymph cannulation is a viable technique for antibiotic disposition studies. A sample of any of the fluids 3 h after injection was representative of the others. While SF concentrations were of limited value for predicting tissue fluid (L) concentrations 3-8 after injection, P concentrations were a useful index." @default.
- W1984025579 created "2016-06-24" @default.
- W1984025579 creator A5013619516 @default.
- W1984025579 creator A5044957202 @default.
- W1984025579 creator A5066432246 @default.
- W1984025579 date "1995-04-01" @default.
- W1984025579 modified "2023-09-26" @default.
- W1984025579 title "The disposition of gentamicin in equine plasma, synovial fluid and lymph" @default.
- W1984025579 cites W1965902363 @default.
- W1984025579 cites W1978758632 @default.
- W1984025579 cites W1991894237 @default.
- W1984025579 cites W1994910485 @default.
- W1984025579 cites W2000444286 @default.
- W1984025579 cites W2020328556 @default.
- W1984025579 cites W2034208256 @default.
- W1984025579 cites W2037224938 @default.
- W1984025579 cites W2047703844 @default.
- W1984025579 cites W2049976577 @default.
- W1984025579 cites W2055970033 @default.
- W1984025579 cites W2057695737 @default.
- W1984025579 cites W2067034394 @default.
- W1984025579 cites W2071669607 @default.
- W1984025579 cites W2071898213 @default.
- W1984025579 cites W2077365277 @default.
- W1984025579 cites W2114422486 @default.
- W1984025579 cites W2118053313 @default.
- W1984025579 cites W2132491970 @default.
- W1984025579 cites W2133864842 @default.
- W1984025579 cites W2166840599 @default.
- W1984025579 cites W2315609346 @default.
- W1984025579 doi "https://doi.org/10.1111/j.1365-2885.1995.tb00565.x" @default.
- W1984025579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7629926" @default.
- W1984025579 hasPublicationYear "1995" @default.
- W1984025579 type Work @default.
- W1984025579 sameAs 1984025579 @default.
- W1984025579 citedByCount "13" @default.
- W1984025579 countsByYear W19840255792013 @default.
- W1984025579 countsByYear W19840255792014 @default.
- W1984025579 countsByYear W19840255792018 @default.
- W1984025579 countsByYear W19840255792020 @default.
- W1984025579 crossrefType "journal-article" @default.
- W1984025579 hasAuthorship W1984025579A5013619516 @default.
- W1984025579 hasAuthorship W1984025579A5044957202 @default.
- W1984025579 hasAuthorship W1984025579A5066432246 @default.
- W1984025579 hasConcept C112705442 @default.
- W1984025579 hasConcept C126322002 @default.
- W1984025579 hasConcept C126894567 @default.
- W1984025579 hasConcept C142724271 @default.
- W1984025579 hasConcept C185592680 @default.
- W1984025579 hasConcept C204787440 @default.
- W1984025579 hasConcept C2775832221 @default.
- W1984025579 hasConcept C2776164576 @default.
- W1984025579 hasConcept C2776268809 @default.
- W1984025579 hasConcept C2779720271 @default.
- W1984025579 hasConcept C501593827 @default.
- W1984025579 hasConcept C55493867 @default.
- W1984025579 hasConcept C71924100 @default.
- W1984025579 hasConceptScore W1984025579C112705442 @default.
- W1984025579 hasConceptScore W1984025579C126322002 @default.
- W1984025579 hasConceptScore W1984025579C126894567 @default.
- W1984025579 hasConceptScore W1984025579C142724271 @default.
- W1984025579 hasConceptScore W1984025579C185592680 @default.
- W1984025579 hasConceptScore W1984025579C204787440 @default.
- W1984025579 hasConceptScore W1984025579C2775832221 @default.
- W1984025579 hasConceptScore W1984025579C2776164576 @default.
- W1984025579 hasConceptScore W1984025579C2776268809 @default.
- W1984025579 hasConceptScore W1984025579C2779720271 @default.
- W1984025579 hasConceptScore W1984025579C501593827 @default.
- W1984025579 hasConceptScore W1984025579C55493867 @default.
- W1984025579 hasConceptScore W1984025579C71924100 @default.
- W1984025579 hasIssue "2" @default.
- W1984025579 hasLocation W19840255791 @default.
- W1984025579 hasLocation W19840255792 @default.
- W1984025579 hasOpenAccess W1984025579 @default.
- W1984025579 hasPrimaryLocation W19840255791 @default.
- W1984025579 hasRelatedWork W1964136109 @default.
- W1984025579 hasRelatedWork W1984025579 @default.
- W1984025579 hasRelatedWork W2025081455 @default.
- W1984025579 hasRelatedWork W2031673194 @default.
- W1984025579 hasRelatedWork W2059925785 @default.
- W1984025579 hasRelatedWork W2412982254 @default.
- W1984025579 hasRelatedWork W2748952813 @default.
- W1984025579 hasRelatedWork W2899084033 @default.
- W1984025579 hasRelatedWork W4242964828 @default.
- W1984025579 hasRelatedWork W47422287 @default.
- W1984025579 hasVolume "18" @default.
- W1984025579 isParatext "false" @default.
- W1984025579 isRetracted "false" @default.
- W1984025579 magId "1984025579" @default.
- W1984025579 workType "article" @default.