Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984063724> ?p ?o ?g. }
- W1984063724 endingPage "587" @default.
- W1984063724 startingPage "581" @default.
- W1984063724 abstract "Depot medroxyprogesterone acetate (DMPA) injectable contraception may decrease bone density and increase the risk for osteoporosis in later life. Prospective data are scarce, especially of the effects of DMPA discontinuation on bone.Between 1994 and 1999, we conducted a population-based prospective cohort study among women enrollees of a Washington State health maintenance organization. We enrolled 457 nonpregnant women, ages 18-39 years (183 DMPA users and 274 non-users). Bone density was measured by dual-energy x-ray absorptiometry every 6 months for 3 years.Bone density decreased notably among DMPA-exposed women at the spine (adjusted mean bone density was -0.0053 gm/cm for DMPA users compared with +0.0023 gm/cm for non-users for each 6-month interval) and total hip (-0.0060 compared with -0.0002 gm/cm ). This represents an annualized mean rate of change at the spine of -0.87% compared with +0.40% and, at the hip, -1.12% compared with -0.05%. Discontinuers of this method (N = 110) showed sizable increases in bone density over comparison women (for each 6-month interval, adjusted mean spine bone density was +0.0067 gm/cm compared with +0.0023 gm/cm, respectively; adjusted mean hip bone density was +0.0035 compared with -0.0002 gm/cm ). Estimated annualized mean rates of change were +1.41% compared with +0.40% [corrected] at the spine and +1.03% [corrected] compared with -0.05% at the hip. After 30 months, mean bone density for discontinuers was similar to that of non-users.In this study, DMPA use was strongly associated with bone density loss. Substantial postdiscontinuation recovery of bone provides evidence that the effects may be largely reversible." @default.
- W1984063724 created "2016-06-24" @default.
- W1984063724 creator A5001077788 @default.
- W1984063724 creator A5011577039 @default.
- W1984063724 creator A5050398259 @default.
- W1984063724 creator A5076423165 @default.
- W1984063724 creator A5081974715 @default.
- W1984063724 date "2002-09-01" @default.
- W1984063724 modified "2023-09-25" @default.
- W1984063724 title "Injectable Hormone Contraception and Bone Density: Results from a Prospective Study" @default.
- W1984063724 cites W1484055082 @default.
- W1984063724 cites W1967872027 @default.
- W1984063724 cites W1970350174 @default.
- W1984063724 cites W1974936404 @default.
- W1984063724 cites W1975525794 @default.
- W1984063724 cites W1976566530 @default.
- W1984063724 cites W1977489294 @default.
- W1984063724 cites W1982942836 @default.
- W1984063724 cites W1986175627 @default.
- W1984063724 cites W1988851330 @default.
- W1984063724 cites W1994690316 @default.
- W1984063724 cites W1995449031 @default.
- W1984063724 cites W1996014843 @default.
- W1984063724 cites W1996058246 @default.
- W1984063724 cites W2000805979 @default.
- W1984063724 cites W2007305494 @default.
- W1984063724 cites W2022499781 @default.
- W1984063724 cites W2037036509 @default.
- W1984063724 cites W2059171787 @default.
- W1984063724 cites W2061644594 @default.
- W1984063724 cites W2069798869 @default.
- W1984063724 cites W2072195133 @default.
- W1984063724 cites W2080162691 @default.
- W1984063724 cites W2080211362 @default.
- W1984063724 cites W2115274031 @default.
- W1984063724 cites W2129388504 @default.
- W1984063724 cites W2142331629 @default.
- W1984063724 cites W2149574073 @default.
- W1984063724 cites W4238045054 @default.
- W1984063724 cites W4244881157 @default.
- W1984063724 cites W4246132361 @default.
- W1984063724 doi "https://doi.org/10.1097/00001648-200209000-00015" @default.
- W1984063724 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12192229" @default.
- W1984063724 hasPublicationYear "2002" @default.
- W1984063724 type Work @default.
- W1984063724 sameAs 1984063724 @default.
- W1984063724 citedByCount "176" @default.
- W1984063724 countsByYear W19840637242012 @default.
- W1984063724 countsByYear W19840637242013 @default.
- W1984063724 countsByYear W19840637242014 @default.
- W1984063724 countsByYear W19840637242015 @default.
- W1984063724 countsByYear W19840637242016 @default.
- W1984063724 countsByYear W19840637242017 @default.
- W1984063724 countsByYear W19840637242018 @default.
- W1984063724 countsByYear W19840637242019 @default.
- W1984063724 countsByYear W19840637242020 @default.
- W1984063724 countsByYear W19840637242021 @default.
- W1984063724 countsByYear W19840637242022 @default.
- W1984063724 countsByYear W19840637242023 @default.
- W1984063724 crossrefType "journal-article" @default.
- W1984063724 hasAuthorship W1984063724A5001077788 @default.
- W1984063724 hasAuthorship W1984063724A5011577039 @default.
- W1984063724 hasAuthorship W1984063724A5050398259 @default.
- W1984063724 hasAuthorship W1984063724A5076423165 @default.
- W1984063724 hasAuthorship W1984063724A5081974715 @default.
- W1984063724 hasBestOaLocation W19840637241 @default.
- W1984063724 hasConcept C126322002 @default.
- W1984063724 hasConcept C131872663 @default.
- W1984063724 hasConcept C141071460 @default.
- W1984063724 hasConcept C188816634 @default.
- W1984063724 hasConcept C2775934596 @default.
- W1984063724 hasConcept C2776306185 @default.
- W1984063724 hasConcept C2776541429 @default.
- W1984063724 hasConcept C2776886416 @default.
- W1984063724 hasConcept C2777164284 @default.
- W1984063724 hasConcept C2778715236 @default.
- W1984063724 hasConcept C2779329777 @default.
- W1984063724 hasConcept C2908647359 @default.
- W1984063724 hasConcept C29456083 @default.
- W1984063724 hasConcept C44249647 @default.
- W1984063724 hasConcept C71924100 @default.
- W1984063724 hasConcept C99454951 @default.
- W1984063724 hasConceptScore W1984063724C126322002 @default.
- W1984063724 hasConceptScore W1984063724C131872663 @default.
- W1984063724 hasConceptScore W1984063724C141071460 @default.
- W1984063724 hasConceptScore W1984063724C188816634 @default.
- W1984063724 hasConceptScore W1984063724C2775934596 @default.
- W1984063724 hasConceptScore W1984063724C2776306185 @default.
- W1984063724 hasConceptScore W1984063724C2776541429 @default.
- W1984063724 hasConceptScore W1984063724C2776886416 @default.
- W1984063724 hasConceptScore W1984063724C2777164284 @default.
- W1984063724 hasConceptScore W1984063724C2778715236 @default.
- W1984063724 hasConceptScore W1984063724C2779329777 @default.
- W1984063724 hasConceptScore W1984063724C2908647359 @default.
- W1984063724 hasConceptScore W1984063724C29456083 @default.
- W1984063724 hasConceptScore W1984063724C44249647 @default.
- W1984063724 hasConceptScore W1984063724C71924100 @default.
- W1984063724 hasConceptScore W1984063724C99454951 @default.