FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984173684> ?p ?o ?g. }

• W1984173684 endingPage "826" @default.
• W1984173684 startingPage "819" @default.
• W1984173684 abstract "The toxicity of o,p'-DDE (1,1-dichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl) ethylene) was evaluated in embryos of medaka (Oryzias latipes) following a one time exposure via nanoinjection. Medaka eggs (early gastrula) were injected with 0.5 nl of triolein (vehicle control) or 0.5 nl of 4 graded doses (0.0005-0.5 ng/egg) of o,p'-DDE in triolein. Embryos were allowed to develop, and fry were reared. Embryonic survival was monitored daily during the first 10 d until hatching and thereafter, on a weekly basis until day 59, at which time the fish were monitored for sexual maturity until day 107. In general, o,p'-DDE caused a dose- and time-dependent mortality. No changes in mortality were observed between the last two time points (day 38 and 59, respectively), and hence a 59 day-LD50 of 346 ng o,p'-DDE/egg was derived from the linear dose-response relationship. Prior to late stage death, only isolated cases of cardiovascular lesions and spinal deformities were observed, but were not dose-dependent. The lowest observable adverse effect level (LOAEL), based on upper 95% CI for regression line=0.0018 mg/kg, and the LOAEL based on exposure doses=0.5 mg/kg. Likewise, the no observable adverse effect level (NOAEL) based on linear extrapolation to 100% survival=0.0000388 mg/kg, while the NOAEL based on exposure doses=0.05 mg/kg. The nanoinjection medaka model has potential in the study of hormonally active compounds in the environment." @default.
• W1984173684 created "2016-06-24" @default.
• W1984173684 creator A5004678963 @default.
• W1984173684 creator A5009044499 @default.
• W1984173684 creator A5026619288 @default.
• W1984173684 creator A5051169764 @default.
• W1984173684 creator A5063086827 @default.
• W1984173684 creator A5066467993 @default.
• W1984173684 creator A5070030918 @default.
• W1984173684 date "2003-12-01" @default.
• W1984173684 modified "2023-09-25" @default.
• W1984173684 title "Toxicity of o,p′-DDE to medaka d-rR strain after a one-time embryonic exposure by in ovo nanoinjection: an early through juvenile life cycle assessment" @default.
• W1984173684 cites W1027874188 @default.
• W1984173684 cites W1967852077 @default.
• W1984173684 cites W1969635484 @default.
• W1984173684 cites W1970491202 @default.
• W1984173684 cites W1977779652 @default.
• W1984173684 cites W1982885726 @default.
• W1984173684 cites W1986311343 @default.
• W1984173684 cites W1988609641 @default.
• W1984173684 cites W1993918361 @default.
• W1984173684 cites W1995388417 @default.
• W1984173684 cites W2000386622 @default.
• W1984173684 cites W2008167507 @default.
• W1984173684 cites W2015205153 @default.
• W1984173684 cites W2027007754 @default.
• W1984173684 cites W2034377896 @default.
• W1984173684 cites W2035794967 @default.
• W1984173684 cites W2048343507 @default.
• W1984173684 cites W2048523718 @default.
• W1984173684 cites W2049464443 @default.
• W1984173684 cites W2067236866 @default.
• W1984173684 cites W2075782267 @default.
• W1984173684 cites W2088804555 @default.
• W1984173684 cites W2091984768 @default.
• W1984173684 cites W2094022965 @default.
• W1984173684 cites W2098805179 @default.
• W1984173684 cites W2116031847 @default.
• W1984173684 cites W2123036062 @default.
• W1984173684 cites W2136948022 @default.
• W1984173684 cites W2139054107 @default.
• W1984173684 cites W2146681664 @default.
• W1984173684 cites W2204134969 @default.
• W1984173684 cites W4232171876 @default.
• W1984173684 cites W4245467786 @default.
• W1984173684 doi "https://doi.org/10.1016/s0045-6535(03)00583-6" @default.
• W1984173684 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14505702" @default.
• W1984173684 hasPublicationYear "2003" @default.
• W1984173684 type Work @default.
• W1984173684 sameAs 1984173684 @default.
• W1984173684 citedByCount "14" @default.
• W1984173684 countsByYear W19841736842012 @default.
• W1984173684 countsByYear W19841736842013 @default.
• W1984173684 countsByYear W19841736842014 @default.
• W1984173684 countsByYear W19841736842017 @default.
• W1984173684 countsByYear W19841736842021 @default.
• W1984173684 crossrefType "journal-article" @default.
• W1984173684 hasAuthorship W1984173684A5004678963 @default.
• W1984173684 hasAuthorship W1984173684A5009044499 @default.
• W1984173684 hasAuthorship W1984173684A5026619288 @default.
• W1984173684 hasAuthorship W1984173684A5051169764 @default.
• W1984173684 hasAuthorship W1984173684A5063086827 @default.
• W1984173684 hasAuthorship W1984173684A5066467993 @default.
• W1984173684 hasAuthorship W1984173684A5070030918 @default.
• W1984173684 hasConcept C115961737 @default.
• W1984173684 hasConcept C126322002 @default.
• W1984173684 hasConcept C140793950 @default.
• W1984173684 hasConcept C18903297 @default.
• W1984173684 hasConcept C196843134 @default.
• W1984173684 hasConcept C2777289358 @default.
• W1984173684 hasConcept C2777495288 @default.
• W1984173684 hasConcept C2777744765 @default.
• W1984173684 hasConcept C2778765379 @default.
• W1984173684 hasConcept C2909208804 @default.
• W1984173684 hasConcept C29730261 @default.
• W1984173684 hasConcept C33070731 @default.
• W1984173684 hasConcept C505870484 @default.
• W1984173684 hasConcept C54355233 @default.
• W1984173684 hasConcept C71924100 @default.
• W1984173684 hasConcept C86803240 @default.
• W1984173684 hasConceptScore W1984173684C115961737 @default.
• W1984173684 hasConceptScore W1984173684C126322002 @default.
• W1984173684 hasConceptScore W1984173684C140793950 @default.
• W1984173684 hasConceptScore W1984173684C18903297 @default.
• W1984173684 hasConceptScore W1984173684C196843134 @default.
• W1984173684 hasConceptScore W1984173684C2777289358 @default.
• W1984173684 hasConceptScore W1984173684C2777495288 @default.
• W1984173684 hasConceptScore W1984173684C2777744765 @default.
• W1984173684 hasConceptScore W1984173684C2778765379 @default.
• W1984173684 hasConceptScore W1984173684C2909208804 @default.
• W1984173684 hasConceptScore W1984173684C29730261 @default.
• W1984173684 hasConceptScore W1984173684C33070731 @default.
• W1984173684 hasConceptScore W1984173684C505870484 @default.
• W1984173684 hasConceptScore W1984173684C54355233 @default.
• W1984173684 hasConceptScore W1984173684C71924100 @default.
• W1984173684 hasConceptScore W1984173684C86803240 @default.
• W1984173684 hasIssue "8" @default.
• W1984173684 hasLocation W19841736841 @default.

• next